DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1213 and Slc2a2

DIOPT Version :9

Sequence 1:	NP_001246937.1	Gene:	CG1213 / 40728	FlyBaseID:	FBgn0037387	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	NP_037011.2	Gene:	Slc2a2 / 25351	RGDID:	3705	Length:	522	Species:	Rattus norvegicus

Alignment Length:	509	Identity:	142/509 - (27%)
Similarity:	228/509 - (44%)	Gaps:	74/509 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 MSPEPVKSGRIFMAAVAANLSAFVVGTTLG------------WTSPIGPKLKSE--------DTS 76
            ||.:.: :|.:......|.|.:|..|..:|            :...:|..|...        :.:
  Rat     1 MSEDKI-TGTLAFTVFTAVLGSFQFGYDIGVINAPQEVIISHYRHVLGVPLDDRRATINYDINGT 64

  Fly    77 DSPL-SRPITSDEDAW------------------ISSLIAVGALVAPFVAGPMADRIGRKWVLL- 121
            |:|| ..|..:..|||                  :|| .|||.:||.|..|.:.|::||...:|
  Rat    65 DTPLIVTPAHTTPDAWEEETEGSAHIVTMLWSLSVSS-FAVGGMVASFFGGWLGDKLGRIKAMLA 128

  Fly   122 --SSSLFFVLAFGLNMVASEVWILYMSRLIQGFGVGFVMTVQPMYVGEISTDNVRGATGSLMQLF 184
              |.||...|..|.:.......::...|.:.|...|.:..:.|||:|||:...:|||.|:|.||.
  Rat   129 ANSLSLTGALLMGCSKFGPAHALIIAGRSVSGLYCGLISGLVPMYIGEIAPTTLRGALGTLHQLA 193

  Fly   185 IVGGILYVYAIG-PYVSYQALQWCCIV----VPVVFD-LVFYMMPESP-YFFAGKGRKSEALKSL 242
            :|.|||.....| .::......|..::    ||.:.. |:....|||| |.:.....:..|.|||
  Rat   194 LVTGILISQIAGLSFILGNQDYWHILLGLSAVPALLQCLLLLFCPESPRYLYLKLEEEVRAKKSL 258

  Fly   243 QFLRGQSAEGVHDEMAEIQANVEEAMA-SKGTVMDLFKNAGNRRALFICAGLISFQQLSGINVVL 306
            :.|||  .|.|..::.|::...|||.. .|.:|:.||.:...|:.:.:...|...||.||||.:.
  Rat   259 KRLRG--TEDVTKDINEMRKEKEEASTEQKVSVIQLFTDPNYRQPIVVALMLHLAQQFSGINGIF 321

  Fly   307 FNSQSIFASANTGLDPAIATIIIGCVQVGSSALTPLVADRLGRKVMLLTS-------SSVMSIGL 364
            :.|.|||.:|... .|..|||.:|.:.:..:|::.|:.::.||:.:.|..       :..||:||
  Rat   322 YYSTSIFQTAGIS-QPVYATIGVGAINMIFTAVSVLLVEKAGRRTLFLAGMIGMFFCAVFMSLGL 385

  Fly   365 AALGAFFYMQLVKGDISSVVWMPVPALIIYNIVYCTGFGPLPWAVLGEMFPANIKSVASSVVAST 429
            ..|..|.:|..|.          :.|:.::...:..|.||:||.::.|.|....:..|.::.|.:
  Rat   386 VLLDKFTWMSYVS----------MTAIFLFVSFFEIGPGPIPWFMVAEFFSQGPRPTALALAAFS 440

  Fly   430 CWTLGFLVTFFYPSL-DALGSYYAFWLFAVCMVVAFFFVLFVVMETKGLSLQQI 482
            .|...|::...:..: |.||. |.|:|||..:::...|..|.|.||||.|..:|
  Rat   441 NWVCNFIIALCFQYIADFLGP-YVFFLFAGVVLIFTLFTFFKVPETKGKSFDEI 493

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1213	NP_001246937.1	SP	42..482	CDD:273317	138/497 (28%)
CG1213	NP_001246937.1	MFS	47..460	CDD:119392	130/470 (28%)
Slc2a2	NP_037011.2	MFS_GLUT_Class1	12..488	CDD:340989	136/490 (28%)
Slc2a2	NP_037011.2	Monosaccharide binding. /evidence=ECO:0000250\|UniProtKB:P11166	312..318		4/5 (80%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100060
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.820