DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1213 and Slc2a3

DIOPT Version :9

Sequence 1:	NP_001246937.1	Gene:	CG1213 / 40728	FlyBaseID:	FBgn0037387	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	XP_006505885.1	Gene:	Slc2a3 / 20527	MGIID:	95757	Length:	495	Species:	Mus musculus

Alignment Length:	488	Identity:	137/488 - (28%)
Similarity:	218/488 - (44%)	Gaps:	43/488 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 EGNTRTMSPEPVKSGRIFMAAVAANLSAFVVGTTLGWTSPIGPKLK-------SEDTSDSPLSRP 83
            |.:...::|.      :..|...|.:.:|..|...|..:.....||       .|...|.|....
Mouse     2 ESSKHNVTPS------LVFAVTVATIGSFQFGYNTGVINAPETILKDFLNYTLEERLEDLPSEGL 60

  Fly    84 ITSDEDAW--ISSLIAVGALVAPFVAGPMADRIGRKWVLLSSSLFFVLA---FGLNMVASEVWIL 143
            :|:   .|  ..::.:||.::..|..|...:|.||:..:|..:|..::|   .|...:|..|.:|
Mouse    61 LTA---LWSLCVAIFSVGGMIGSFSVGLFVNRFGRRNSMLLVNLLAIIAGCLMGFAKIAESVEML 122

  Fly   144 YMSRLIQGFGVGFVMTVQPMYVGEISTDNVRGATGSLMQLFIVGGILYV------YAIGPYVSYQ 202
            .:.||:.|...|......|||:||:|...:|||.|:|.||.||.|||..      :.:|....:.
Mouse   123 ILGRLLIGIFCGLCTGFVPMYIGEVSPTALRGAFGTLNQLGIVVGILVAQIFGLDFILGSEELWP 187

  Fly   203 ALQWCCIVVPVVFDLVFYMMPESPYF-FAGKGRKSEALKSLQFLRGQSAEGVHDEMAEIQANVEE 266
            .|....|:..::........||||.| ...|..:.:|.:.||.|.|.|     |.:.|||...:|
Mouse   188 GLLGLTIIPAILQSAALPFCPESPRFLLINKKEEDQATEILQRLWGTS-----DVVQEIQEMKDE 247

  Fly   267 AM----ASKGTVMDLFKNAGNRRALFICAGLISFQQLSGINVVLFNSQSIFASANTGLDPAIATI 327
            ::    ..:.||::||::....:.|.|...|...|||||||.|.:.|..||..|.. .:|..|||
Mouse   248 SVRMSQEKQVTVLELFRSPNYVQPLLISIVLQLSQQLSGINAVFYYSTGIFKDAGV-QEPIYATI 311

  Fly   328 IIGCVQVGSSALTPLVADRLGRKVMLLTSSSVMSIGLAALGAFFYMQ-LVKGDISSVVWMPVPAL 391
            ..|.|....:.::..:.:|.||:.:.:....    |:|....|..:. |:|.|..::.::.:.|:
Mouse   312 GAGVVNTIFTVVSLFLVERAGRRTLHMIGLG----GMAVCSVFMTISLLLKDDYEAMSFVCIVAI 372

  Fly   392 IIYNIVYCTGFGPLPWAVLGEMFPANIKSVASSVVASTCWTLGFLVTFFYPSLDALGSYYAFWLF 456
            :||...:..|.||:||.::.|:|....:..|.:|.....||..|||...:||..|....|.|.:|
Mouse   373 LIYVAFFEIGPGPIPWFIVAELFSQGPRPAAIAVAGCCNWTSNFLVGMLFPSAAAYLGAYVFIIF 437

  Fly   457 AVCMVVAFFFVLFVVMETKGLSLQQIQDRLNGK 489
            |..::....|..|.|.||||.:.:.|.....|:
Mouse   438 AAFLIFFLIFTFFKVPETKGRTFEDIARAFEGQ 470

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1213	NP_001246937.1	SP	42..482	CDD:273317	133/463 (29%)
CG1213	NP_001246937.1	MFS	47..460	CDD:119392	125/436 (29%)
Slc2a3	XP_006505885.1	MFS_GLUT_Class1	14..458	CDD:340989	132/456 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100060
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810