DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1213 and K08H10.6

DIOPT Version :9

Sequence 1:	NP_001246937.1	Gene:	CG1213 / 40728	FlyBaseID:	FBgn0037387	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	NP_505572.1	Gene:	K08H10.6 / 187181	WormBaseID:	WBGene00010698	Length:	479	Species:	Caenorhabditis elegans

Alignment Length:	482	Identity:	115/482 - (23%)
Similarity:	209/482 - (43%)	Gaps:	44/482 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 RTMSPEPVKSGRIFMAAVAANLS-AFVVGTTLGWTSPIGPKLKS--EDTSDSPLSRPITSDEDAW 91
            |.:...|..:.|:...:|.|..: .|..|..:...:|:...|:.  .|...:..|..::|.:.:.
Worm     8 RNLETPPHLTTRLLATSVVATFAGGFHFGYLISAVNPLSEILQQFIVDNLQNRYSYELSSSQLSL 72

  Fly    92 ISSLIA----VGALVAPFVAGPMADRIG-RKWVLLSS--SLFFVLAFGLNMVASEVWILYMSRLI 149
            |.|.:|    :||::..:::..:...|| |..:||::  .||....|||........:|.:||::
Worm    73 IWSSLAGCLFIGAMIGAYISIFLLQSIGPRNSLLLAAILQLFSAPVFGLAYSLRLCELLPISRIL 137

  Fly   150 QGFGVGFVMTVQPMYVGEISTDNVRGATGSLMQLFIVGGILYVYA--IG-PYVSYQALQWCCI-- 209
            .|......::.|.:::.|||....||.|.||..|  :|...::.|  :| |||.....||..|
Worm   138 SGIAFAIGISAQGVFLTEISPAKFRGLTNSLSGL--IGNCAFLLAATLGTPYVLGTVTQWKYIFF 200

  Fly   210 --VVPVVFDLVFYM--MPESPYFFAGKGRKSEALKSLQFLRGQSA--EGVHDEMAEIQANVEEAM 268
              .:|.|..::..:  ..:||.:....|:.||...:::...|::.  :.:.:::..|...|:|.
Worm   201 IETIPCVLHILVNITTFHDSPTYLLSIGKISEGESAIKVYYGETCHIKKIMEDLRIIDNGVKEK- 264

  Fly   269 ASKGTVMDLFKNAGNRRALFICAGLISFQQLSGINVVLFNSQSIFASANTGLDP---AIATIIIG 330
                ::..:.|:.|..:||.:...:......|||..:.|  ...|.....|..|   |:|..:..
Worm   265 ----SLRQILKDKGCAQALSLAVAINFSVAFSGIVAISF--FGTFLLQTIGFSPEGSAVANSLCS 323

  Fly   331 CVQVGSSALTPLVADRLGRKVMLLTSSSVMSIGLAALGAFFYMQLV----KGDISSVVWMPVPAL 391
            ...:.|:.|..:..|::||:.:|:||..|:     ||...|.|.||    ....|.:.|..:...
Worm   324 FASIVSALLAAIAMDKIGRRPLLITSLLVL-----ALINIFMMSLVFLYDSTKDSFLAWPFLALF 383

  Fly   392 IIYNIVYCTGFGPLPWAVLGEMFPANIKSVASSVVASTCWTLGFLVTFFYPSL-DALGSYYAFWL 455
            :::..|:..|.||....:..|:.|....|...|...|..:...|:....|..| :::|. :||.|
Worm   384 VLFTFVFSIGIGPAAVFIGAELAPPGTISKMQSYSTSVQFAGSFICPIIYLQLVESIGG-FAFML 447

  Fly   456 FAVCMVVAFFFVLFVVMETKGLSLQQI 482
            |.|.:.:...:....:.||||.|..:|
Worm   448 FIVPLTITAAYFYMYLPETKGKSPVEI 474

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1213	NP_001246937.1	SP	42..482	CDD:273317	111/468 (24%)
CG1213	NP_001246937.1	MFS	47..460	CDD:119392	106/441 (24%)
K08H10.6	NP_505572.1	MFS_GLUT_Class1_2_like	24..469	CDD:340915	109/459 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D524131at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920