DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1213 and R09B5.11

DIOPT Version :9

Sequence 1:	NP_001246937.1	Gene:	CG1213 / 40728	FlyBaseID:	FBgn0037387	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	NP_503413.2	Gene:	R09B5.11 / 178634	WormBaseID:	WBGene00019979	Length:	516	Species:	Caenorhabditis elegans

Alignment Length:	527	Identity:	134/527 - (25%)
Similarity:	232/527 - (44%)	Gaps:	79/527 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 SISREEETGVQYSYTEVSTFQIREGNTRTMSPEPVKSGRIFMAAVAANLSAFVVGTTLGWTSPIG 67
            ::..|..:.|:.|..|         |.....|:...:..:|....:..|::|..|..:|..:..|
Worm    17 NMESESSSNVEKSEKE---------NHHQSLPDENWTPFLFFCISSIALASFQDGFQIGCINAPG 72

  Fly    68 P-------KLKSEDTSDSPLSRPITSDEDA---W--ISSLIAVGALVAPFVAGPMADRIGRKWVL 120
            |       |...|      |...:.|...|   |  ..|:.:||.:...|.:|.:||:.|||..|
Worm    73 PLIIDWIKKCHFE------LFGEVLSQYQADFIWSVAVSMFSVGGMFGSFCSGFLADKFGRKSTL 131

  Fly   121 LSSSLFFVLAFGLNMVASEVWILY----MSRLIQGFGVGFVMTVQPMYVGEISTDNVRGATGSLM 181
            |.:::..:|| .:.:..|:::..|    ..|.:.|...|....:.||::.|::..|:||..||..
Worm   132 LYNNILALLA-AVCLSTSKLFNFYPMIVFGRFLVGLNCGITSGLVPMFLTELAPANLRGKCGSFH 195

  Fly   182 QLFIVGGILYVYAIG-----------PYVSYQALQWCCIVVPVVFDLVFYMMP---ESPYFFAGK 232
            ||.|...|:...|:|           ||:      :.|:.:|....|.  .:|   |||.:...|
Worm   196 QLNISVAIVLSQALGLPQIFGTQVGWPYI------FACVAIPTFLQLA--TIPFCVESPKYLISK 252

  Fly   233 -GRKSEALKSLQFLRGQSAEGVHDEMAEIQANVEEAMAS-----KGTVMDLFKNAGNRRALFICA 291
             ..:.||.:.|:.|||.:..   ||  |::..|:|.|.:     :...:.|||  |:.:...|.:
Worm   253 LNDREEARRILEKLRGHTKV---DE--ELEHMVQETMVTVEPLHQPGYVSLFK--GDNQWPMIVS 310

  Fly   292 GLISF-QQLSGINVVLFNSQSIF-ASANTGLDPAIATIIIGCVQVGSSALTPLVAD--RLGRKVM 352
            .|:.| ||.|||:.|.|.|..|| .:..:|.:|..||:..||:::.::.....:.|  :.|||.:
Worm   311 ILMMFSQQFSGISAVTFYSTLIFKRNGLSGNEPMYATVGFGCIKLIATFGCLFLIDHPKFGRKRL 375

  Fly   353 LLTSSSVMSIGLAALGAFFYMQLVKGDISSVVWMPVPALIIYNIVYCTGFGPLPWAVLGEMFPAN 417
            .:...|.|.|  :::.....:.|.........:|.|..::.:.:.:..|.||:||....|:|.:.
Worm   376 HIAGLSGMCI--SSILIVITLTLSNAGYHWASYMNVLFILSFVVTFAFGPGPIPWFFTSELFDSA 438

  Fly   418 IKSVASSVVASTCWTLGFLVTFFYPSLDALGSYYAFWLFAVCMVVAFFFVLFV---VMETKGLSL 479
            .:..|::|.|::.|...::|...:..::.:...|||.:|.   ...|.|.:|.   |.||||.|.
Worm   439 TRGRAAAVSATSNWVANWMVGLTFLPINNIIHQYAFLMFT---FFTFTFAIFTWKFVPETKGKSP 500

  Fly   480 QQIQDRL 486
            ..|:..|
Worm   501 SAIRKEL 507

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1213	NP_001246937.1	SP	42..482	CDD:273317	126/482 (26%)
CG1213	NP_001246937.1	MFS	47..460	CDD:119392	116/452 (26%)
R09B5.11	NP_503413.2	Sugar_tr	54..499	CDD:278511	124/471 (26%)
R09B5.11	NP_503413.2	MFS	90..465	CDD:119392	103/392 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100060
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810