DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1213 and fgt-1

DIOPT Version :9

Sequence 1:	NP_001246937.1	Gene:	CG1213 / 40728	FlyBaseID:	FBgn0037387	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	NP_493982.1	Gene:	fgt-1 / 173525	WormBaseID:	WBGene00019207	Length:	510	Species:	Caenorhabditis elegans

Alignment Length:	512	Identity:	154/512 - (30%)
Similarity:	247/512 - (48%)	Gaps:	53/512 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 SISREEETGVQYSYTEVSTFQIREGNTRTMSPEPVKSGRIFMAAVAANLSAFVVGTTLGWTSPIG 67
            |:|...::...||....:|.:|       :.|:...:..:..:|....|::|..|..:|..:..|
Worm    14 SLSDSSKSPSSYSTPGTTTQKI-------IFPDGKLTKCLAFSAFVITLASFQFGYHIGCVNAPG 71

  Fly    68 PKL------KSEDTSDSPLSRPITSDEDAW--ISSLIAVGALVAPFVAGPMADRIGRKWVLLSSS 124
            ..:      ..:|..|..|||  .:.:.||  ..|:.|||.::....:|.:||::||:..|..::
Worm    72 GLITEWIIGSHKDLFDKELSR--ENADLAWSVAVSVFAVGGMIGGLSSGWLADKVGRRGALFYNN 134

  Fly   125 LFFVLAFGLNMVASEVW---ILYMSRLIQGFGVGFVMTVQPMYVGEISTDNVRGATGSLMQLFIV 186
            |..:.|..|..:|..|.   ::.:.|||.|...||...:.||::.|||.:|:||..|||.||.:.
Worm   135 LLALAAAALMGLAKSVGAYPMVILGRLIIGLNCGFSSALVPMFLTEISPNNLRGMLGSLHQLLVT 199

  Fly   187 GGILYVYAIG-PYVSYQALQWCCI----VVPVVFDLVFYMM-PESP-YFFAGKGRKSEALKSLQF 244
            ..||.....| |::.....:|..|    |||.|..|...|: |||| |..|.:|:::||..:|:.
Worm   200 IAILVSQIFGLPHLLGTGDRWPLIFAFTVVPAVLQLALLMLCPESPKYTMAVRGQRNEAESALKK 264

  Fly   245 LRGQSAEGVHDEMAEIQANVEEAMAS----KGTVMDLFKNAGNRRALF---ICAGLISFQQLSGI 302
            ||     ...|...||:|..|||.|:    |..:.|:||.|    .|:   |...::..||||||
Worm   265 LR-----DTEDVSTEIEAMQEEATAAGVQEKPKMGDMFKGA----LLWPMSIAIMMMLAQQLSGI 320

  Fly   303 NVVLFNSQSIFASAN-TGLDPAIATIIIGCVQVGSSALTPLVAD--RLGRKVMLLTSSSVMSIGL 364
            ||.:|.|..||..|. ||.:|..|||.:|.|.|..:.::..:.|  :.||:.:||...:.|.:..
Worm   321 NVAMFYSTVIFRGAGLTGNEPFYATIGMGAVNVIMTLISVWLVDHPKFGRRSLLLAGLTGMFVST 385

  Fly   365 AALGAFFYMQLVKGDISSVVWMPVPAL---IIYNIVYCTGFGPLPWAVLGEMFPANIKSVASSVV 426
            ..|.....:|...||    .|....|:   :::.|.:.||.|.:||..:.|:|.::.:..|:|:.
Worm   386 LLLVGALTIQNSGGD----KWASYSAIGFVLLFVISFATGPGAIPWFFVSEIFDSSARGNANSIA 446

  Fly   427 ASTCWTLGFLVTFFYPSLDALGSYYAFWLFAVCMVVAFFFVLFVVMETKGLSLQQIQ 483
            ....|....||...:..::.|...|:|::|:..:....|:....|.||||.|::|||
Worm   447 VMVNWAANLLVGLTFLPINNLMQQYSFFIFSGFLAFFIFYTWKFVPETKGKSIEQIQ 503

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1213	NP_001246937.1	SP	42..482	CDD:273317	144/470 (31%)
CG1213	NP_001246937.1	MFS	47..460	CDD:119392	136/443 (31%)
fgt-1	NP_493982.1	Sugar_tr	50..506	CDD:278511	147/469 (31%)
fgt-1	NP_493982.1	MFS	100..491	CDD:119392	125/403 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100060
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810