Protein Alignment CG1213 and SLC2A12

DIOPT Version :9

• Sequence 1: NP_001246937.1
• Gene: CG1213 / 40728
• FlyBaseID: FBgn0037387
• Length: 491
• Species: Drosophila melanogaster
• Sequence 2: NP_660159.1
• Gene: SLC2A12 / 154091
• HGNCID: 18067
• Length: 617
• Species: Homo sapiens
• Alignment Length: 579
• Identity: 139/579 - (24%)
• Similarity: 244/579 - (42%)
• Gaps: 118/579 - (20%)

  Fly     2 PSISREEETGVQYSYTEVSTFQIREGNTRTMSPEPVKSGRI-FMAAVAANLSAFVVGTTLGWTSP 65
            ||:..::.|.|:           .||:.....|.....|.. |:::|.|.:|..:||..||..|.
Human    10 PSLLNQKGTAVE-----------TEGSGSRHPPWARGCGMFTFLSSVTAAVSGLLVGYELGIISG 63

  Fly    66 IGPKLKSEDTSDSPLSRPITSDEDAWISSLIAVGALVAPFVAGPMADRIGRKWVLLSSSLFFVLA 130
            ...::|:       |......:::..:|||: :|||:|....|.:.||.||:..::.||....|.
Human    64 ALLQIKT-------LLALSCHEQEMVVSSLV-IGALLASLTGGVLIDRYGRRTAIILSSCLLGLG 120

  Fly   131 FGLNMVASEVWILYMSRLIQGFGVGFVMTVQPMYVGEISTDNVRGATGSLMQLFIVGGILYVYAI 195
            ..:.:::....:|.:.|:..|..:........:|:.||:..:.||...||.:|.||.|||..| |
Human   121 SLVLILSLSYTVLIVGRIAIGVSISLSSIATCVYIAEIAPQHRRGLLVSLNELMIVIGILSAY-I 184

  Fly   196 GPYVSYQALQ-W---CCIVVP--VVFDLVFYMMPESPYFFAGKGRKSEALKSLQFLRGQSAEGVH 254
            ..|....... |   ..:|:|  |:..:..|.:|.||.|...||::..|.|.|..||..|  ...
Human   185 SNYAFANVFHGWKYMFGLVIPLGVLQAIAMYFLPPSPRFLVMKGQEGAASKVLGRLRALS--DTT 247

  Fly   255 DEMAEIQANVEEAMASKGTVMDLFKNAGNRRA-LFICAGLISFQQLSGINVVLFNSQSIFASANT 318
            :|:..|::::::..  :.:..|||::..|.|. :.|...|:.|.|::|...:||.:.::..|...
Human   248 EELTVIKSSLKDEY--QYSFWDLFRSKDNMRTRIMIGLTLVFFVQITGQPNILFYASTVLKSVGF 310

  Fly   319 GLDPA--IATIIIGCVQVGSSALTPLVADRLGRKVMLLTSSSVMSIGLAALG------------- 368
            ..:.|  :|:..:|.|:|.|:....|:.|.:|.|..|...||||:..|..:|
Human   311 QSNEAASLASTGVGVVKVISTIPATLLVDHVGSKTFLCIGSSVMAASLVTMGIVNLNIHMNFTHI 375

  Fly   369 -------------AFFY------------------------------------------------ 372
                         :..|
Human   376 CRSHNSINQSLDESVIYGPGNLSTNNNTLRDHFKGISSHSRSSLMPLRNDVDKRGETTSASLLNA 440

  Fly   373 ------MQLV--KGDISSVV-WMPVPALIIYNIVYCTGFGPLPWAVLGEMFPANIKSVASSVVAS 428
                  .|:|  .||:.:.: |:.:.:|::|...:..|.||:||.||.|:||..|:..|.::.:|
Human   441 GLSHTEYQIVTDPGDVPAFLKWLSLASLLVYVAAFSIGLGPMPWLVLSEIFPGGIRGRAMALTSS 505

  Fly   429 TCWTLGFLVTF-FYPSLDALGSYYAFWLFAVCMVVAFFFVLFVVMETKGLSLQQIQDRL 486
            ..|.:..|::. |....|.:|..:..:::.:..:.:..||:..:.||||.||:||...|
Human   506 MNWGINLLISLTFLTVTDLIGLPWVCFIYTIMSLASLLFVVMFIPETKGCSLEQISMEL 564

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1213	NP_001246937.1	SP	42..482	CDD:273317	128/533 (24%)
		MFS	47..460	CDD:119392	119/505 (24%)
SLC2A12	NP_660159.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..29		6/29 (21%)
		Sugar_tr	44..561	CDD:306568	128/529 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S3740
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.770