DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1213 and SLC2A14

DIOPT Version :9

Sequence 1:	NP_001246937.1	Gene:	CG1213 / 40728	FlyBaseID:	FBgn0037387	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	NP_001273166.1	Gene:	SLC2A14 / 144195	HGNCID:	18301	Length:	535	Species:	Homo sapiens

Alignment Length:	497	Identity:	133/497 - (26%)
Similarity:	212/497 - (42%)	Gaps:	74/497 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 EPVKSGRIFMAAVAANLSAFVVGTTLGWTSPIGPKLKS------EDTSDSPLSRPITSDEDAWIS 93
            |.|....|| |...|.:.:|..|...|..:.....:|.      .|.:::|.|..:.::..:...
Human    43 EEVTPALIF-AITVATIGSFQFGYNTGVINAPETIIKEFINKTLTDKANAPPSEVLLTNLWSLSV 106

  Fly    94 SLIAVGALVAPFVAGPMADRIGRKWVLLSSSLFFVLA---FGLNMVASEVWILYMSRLIQGFGVG 155
            ::.:||.::..|..|...:|.||:..:|..:|.....   .||..:|..|.:|.:.||:.|...|
Human   107 AIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAATGGCLMGLCKIAESVEMLILGRLVIGLFCG 171

  Fly   156 FVMTVQPMYVGEISTDNVRGATGSLMQLFIVGGILYVYAIG--------------------PYVS 200
            ......|||:||||...:|||.|:|.||.||.|||.....|                    |.:.
Human   172 LCTGFVPMYIGEISPTALRGAFGTLNQLGIVIGILVAQIFGLELILGSEELWPVLLGFTILPAIL 236

  Fly   201 YQALQWCCIVVPVVFDLVFYMMPESPYFFAGKGRKSE-ALKSLQFLRG-----QSAEGVHDEMAE 259
            ..|...||              ||||.|.....:|.| |.:.||.|.|     |..:.:.||.|.
Human   237 QSAALPCC--------------PESPRFLLINRKKEENATRILQRLWGTQDVSQDIQEMKDESAR 287

  Fly   260 IQANVEEAMASKGTVMDLFKNAGNRRALFICAGLISFQQLSGINVVLFNSQSIFASANTGLDPAI 324
            :      :...:.||::||:.:..|:.:.|...|...|||||||.|.:.|..||..|.. ..|..
Human   288 M------SQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGV-QQPIY 345

  Fly   325 ATIIIGCVQVGSSALTPLVADRLGRKVM-------LLTSSSVMSIGLAALGAFFYMQLVKGDISS 382
            |||..|.|....:.|:..:.:|.||:.:       :...|::|::.|          |:|...:.
Human   346 ATISAGVVNTIFTLLSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSL----------LLKNHYNG 400

  Fly   383 VVWMPVPALIIYNIVYCTGFGPLPWAVLGEMFPANIKSVASSVVASTCWTLGFLVTFFYPSLDAL 447
            :.::.:.|::::...:..|.||:||.::.|:|....:..|.:|...:.||..|||...:||....
Human   401 MSFVCIGAILVFVACFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPSAAYY 465

  Fly   448 GSYYAFWLFAVCMVVAFFFVLFVVMETKGLSLQQIQDRLNGK 489
            ...|.|.:|...::....|..|.|.||:|.:.:.|.....|:
Human   466 LGAYVFIIFTGFLITFLAFTFFKVPETRGRTFEDITRAFEGQ 507

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1213	NP_001246937.1	SP	42..482	CDD:273317	129/481 (27%)
CG1213	NP_001246937.1	MFS	47..460	CDD:119392	120/454 (26%)
SLC2A14	NP_001273166.1	MFS	53..487	CDD:119392	121/464 (26%)
SLC2A14	NP_001273166.1	Sugar_tr	54..504	CDD:278511	127/480 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100060
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810