DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1213 and slc2a4

DIOPT Version :9

Sequence 1:	NP_001246937.1	Gene:	CG1213 / 40728	FlyBaseID:	FBgn0037387	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	XP_031755513.1	Gene:	slc2a4 / 101731550	XenbaseID:	XB-GENE-5943313	Length:	509	Species:	Xenopus tropicalis

Alignment Length:	493	Identity:	127/493 - (25%)
Similarity:	233/493 - (47%)	Gaps:	47/493 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 IREGNTRTMSPEPVKSGRIFMAAVAANLSAFVVGTTLG-WTSPIGPKLKSEDTSDSPLSRPITSD 87
            :|.|.|:|          :.::...|.|.:|..|..:| ..:|  .|:..:..::|.:||  :|.
Frog    16 VRSGVTKT----------LVLSVFTAILGSFQFGYNIGVINAP--QKIIEQSYNESWISR--SSS 66

  Fly    88 EDAWIS------------SLIAVGALVAPFVAGPMADRIGRKWVLLSSSLFFVLA---FGLNMVA 137
            ..|.|.            ::.::|.:|:....|.::..:|||..::.:::|..||   .||:.|.
Frog    67 GSASIDPGLLRTLWSLSVAIFSIGGMVSSLSVGVVSQWLGRKRAMVINNVFAFLAGSFMGLSQVC 131

  Fly   138 SEVWILYMSRLIQGFGVGFVMTVQPMYVGEISTDNVRGATGSLMQLFIVGGILYVYA------IG 196
            ....::.:.|.:.|...|....:.||||||||..::|||.|:|.||.:|.|||....      :|
Frog   132 QSYEMMIVGRFLIGVYSGLASGLVPMYVGEISPTHLRGAMGTLHQLSLVIGILVAQVLGLELFLG 196

  Fly   197 PYVSYQALQWCCIVVPVVFDLVFYMMPESPYF-FAGKGRKSEALKSLQFLRGQSAEGVHDEMAEI 260
            ....:.||.|..::...:..|:....||||.| :....::::|.|||:.|.|  ...|.|:::::
Frog   197 TNTRWPALFWVTLIPAALQCLMLPFCPESPRFLYIVCEQEAQAKKSLRRLTG--LPDVTDDLSDM 259

  Fly   261 QANVEEAMAS-KGTVMDLFKNAGNRRALFICAGLISFQQLSGINVVLFNSQSIFASANTGLD-PA 323
            :....:..:. |.:::.:|::...|:.:.:...|...|||||||.:.:.|..||:.|  |:: |.
Frog   260 KEEKRQMDSEPKVSILQIFRSRNYRQPILVAIVLQLSQQLSGINAIFYYSTDIFSKA--GVEQPI 322

  Fly   324 IATIIIGCVQVGSSALTPLVADRLGRKVMLLTSSSVMSIGLAALGAFFYMQLVKGDISSVVWMPV 388
            .|||..|.|....:.::..:.:|.||:.:.|...:.|.:....:.|...:|   ..:.|:.::.:
Frog   323 YATIGAGIVNTAFTVVSLFLVERAGRRTLQLLGLAGMIVCALLMTAAMVLQ---ESVPSLSYLSM 384

  Fly   389 PALIIYNIVYCTGFGPLPWAVLGEMFPANIKSVASSVVASTCWTLGFLVTFFYPSLDALGSYYAF 453
            .|:..:...:..|.||:||.::.|:|....:..|.::...|.||..|::...:..:..|...|.|
Frog   385 AAIFGFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAIAGCTNWTSNFIIGMGFQYVAELCGPYVF 449

  Fly   454 WLFAVCMVVAFFFVLFVVMETKGLSLQQIQDRLNGKRN 491
            .||...:.....|..|.|.||:|.|..:|..... :||
Frog   450 LLFGALLFAFLIFTYFRVPETRGRSFDEISHAFR-RRN 486

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1213	NP_001246937.1	SP	42..482	CDD:273317	120/464 (26%)
CG1213	NP_001246937.1	MFS	47..460	CDD:119392	113/437 (26%)
slc2a4	XP_031755513.1	MFS_GLUT_Class1	26..473	CDD:340989	118/457 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010