DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1213 and slc2a3

DIOPT Version :9

Sequence 1:	NP_001246937.1	Gene:	CG1213 / 40728	FlyBaseID:	FBgn0037387	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	XP_031762189.1	Gene:	slc2a3 / 100497763	XenbaseID:	XB-GENE-921721	Length:	499	Species:	Xenopus tropicalis

Alignment Length:	475	Identity:	129/475 - (27%)
Similarity:	220/475 - (46%)	Gaps:	45/475 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 KSGRIFMAAVAANLSAFVVGTTLGWTSPI--GPK--LKS-----------EDTSDSPLSRPITSD 87
            :.|||..:.|.|...|.:.....|:.:.:  .|:  :||           ::.|:|.|:
Frog    11 QEGRITCSLVFAVCVAAIGSLQFGYNTGVINAPEKIIKSFYNGTYEHRYGKEISESLLT------ 69

  Fly    88 EDAWISS--LIAVGALVAPFVAGPMADRIGRKWVLLSSSLFFVLA---FGLNMVASEVWILYMSR 147
             ..|..|  :.:||.:|.....|..|:|.||:..:|..::..::.   .|.:.:|....:|.:.|
Frog    70 -SLWSLSVAIFSVGGMVGSLSVGFFANRFGRRNAMLLVNVAAIVGGVFMGFSKLAWSPEMLIIGR 133

  Fly   148 LIQGFGVGFVMTVQPMYVGEISTDNVRGATGSLMQLFIVGGILYV------YAIGPYVSYQALQW 206
            .|.|...|....:.|||:||::..::|||.|:|.||.||.|||..      :.:|....:..|..
Frog   134 FIIGIFCGLCTGLVPMYIGELAPTSLRGALGTLNQLGIVVGILVAQIFGLEFILGSETLWPLLLG 198

  Fly   207 CCIVVPVVFDLVFYMMPESP-YFFAGKGRKSEALKSLQFLRGQSAEGVHDEMAEIQANVEEAMAS 270
            ..:.:.::..::....|||| |....|....:|.:.|:.|||.:  .|..::.|::.......|.
Frog   199 LTVFLSIIQCVLLPFCPESPRYLLIVKKEDEKAERILRKLRGTT--DVASDVQEMKDESARTAAE 261

  Fly   271 KG-TVMDLFKNAGNRRALFICAGLISFQQLSGINVVLFNSQSIFASANTGLDPAIATIIIGCVQV 334
            |. :::::|:::..|:.:.|...|...|||||||.|.:.|.|||..|... :|..|||..|.|..
Frog   262 KSVSILEIFRSSQYRQPITIAIILQLSQQLSGINAVFYYSTSIFEDAGVP-NPVYATIGAGVVNT 325

  Fly   335 GSSALTPLVADRLGRKVMLLTSSSVMSIGLAALGAFFYMQLVKGDISSVVWMPVPALIIYNIV-- 397
            ..:.::.|:.:|.||:.:.||     .:|..|:||......:|.......|..|..:.||..|
Frog   326 VFTVVSLLIVERAGRRTLQLT-----GLGGMAVGALIMTIALKLKEQDQAWSYVSIVAIYCFVAL 385

  Fly   398 YCTGFGPLPWAVLGEMFPANIKSVASSVVASTCWTLGFLVTFFYPSLDALGSYYAFWLFAVCMVV 462
            :..|.||:||.::.|:|....:..|.::...:.||..|||...:|........|.|.:|.|.:::
Frog   386 FEIGPGPIPWFIVAELFSQGPRPAAMAISGCSNWTANFLVGMLFPYAAKGCGPYVFLIFMVLLIL 450

  Fly   463 AFFFVLFVVMETKGLSLQQI 482
            .|.:..|.|.||:|.:.:.|
Frog   451 FFIYTFFKVPETRGRTFEDI 470

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1213	NP_001246937.1	SP	42..482	CDD:273317	126/469 (27%)
CG1213	NP_001246937.1	MFS	47..460	CDD:119392	119/442 (27%)
slc2a3	XP_031762189.1	MFS_GLUT_Class1	21..465	CDD:340989	123/458 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000