DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1213 and slc2a11.2

DIOPT Version :9

Sequence 1:	NP_001246937.1	Gene:	CG1213 / 40728	FlyBaseID:	FBgn0037387	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	NP_001339156.1	Gene:	slc2a11.2 / 100496725	XenbaseID:	XB-GENE-5857129	Length:	489	Species:	Xenopus tropicalis

Alignment Length:	509	Identity:	135/509 - (26%)
Similarity:	220/509 - (43%)	Gaps:	99/509 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 VKSGRIFMAAVAANLSAFVVGTTLGWTSPIGPKLK------------SEDTSDSPLSRPITSDED 89
            |.||::.:     ||:...:...:|.|...|..:.            ..||.......|:..|:.
Frog     5 VHSGKLTL-----NLTLLCLVLGIGGTFQYGLHISLINSPAEYIQKFINDTWQHRYGSPLHPDKI 64

  Fly    90 ----AWISSLIAVGALVAPFVAGPMADRIGRKWVLLSSSLFFVLAFGLNM---VASEVWILYMSR 147
                ::|.|:.::|.|:...:.|.::...|||...|.:::|.:|...|.|   ||....::.:.|
Frog    65 TLFWSFIVSVYSIGGLMGSLIVGYLSVSFGRKKTQLYNNVFALLGAALMMLSPVAQSFEMIIVGR 129

  Fly   148 LIQGFGVGFVMTVQPMYVGEISTDNVRG---------ATGSLMQLFIVG--GILYVYAIGPY-VS 200
            .:.|...|..:.:..||:||.:...:||         |.|.||. |:||  ..|...|:.|| :|
Frog   130 FLYGVNTGVSLNLHTMYIGECAPKKLRGISVTVSLFIALGKLMG-FVVGLREFLGSEALWPYLMS 193

  Fly   201 YQALQWCCIVVPVVFDLV---FYMMPESP-YFFAGKGRKSEALKSLQFLRGQSAEGVHDEMAEI- 260
            :.|       ||.:..|:   |:  |||| |....|..|...||::|.|.|..     |.:||:
Frog   194 FSA-------VPALVQLLTLPFF--PESPRYLLIDKDNKEGCLKAMQQLWGAG-----DHVAEMD 244

  Fly   261 ----QANVEEAMASKGTVMDLFKNAGNR---RALFICAGLISFQQLSGINVVLFNSQSIFASA-- 316
                :.|..|....|| ||||.|....|   .::.:..|.|   ||:|||||.|.:..:|.:|
Frog   245 DMLAEKNSLEGEQRKG-VMDLLKKRCVRWQMISIVLTCGAI---QLTGINVVYFYAYDVFRNAGI 305

  Fly   317 ----------NTGLDPAIATIIIGCVQVGSSALTPLVADRLGRKVMLLTSSSVMSIGLAALGAFF 371
                      ..|:..|:.|::.|           .|.||:|||.:|..:..|:::.|:.|.|..
Frog   306 PDRQIPFISLGIGVTEALTTVLCG-----------FVIDRMGRKPLLWINYGVITLTLSLLTATL 359

  Fly   372 YMQLVKGDISSVVWMPV--PALI-IYNIVYCTGFGPLPWAVLGEMFPANIKSVASSVVASTCWTL 433
            .:|    |:.|  |||.  .||| |:.:.:..|.|.:...:..|||..:.:..|..::....|..
Frog   360 SLQ----DLHS--WMPYFSSALIFIFTLSFGLGPGGVSCVIPTEMFVQSYRPAAYMLIGILNWLG 418

  Fly   434 GFLVTFFYPSLDALGSYYAFWLFAVCMVVAFFFVLFVVMETKGLSLQQIQDRLN 487
            .|::.:.:|.::|....:.|..|.:..:....|...::.|||..|:.:|.|..|
Frog   419 MFILAWSFPFMEAALGAFCFVFFIILCICMGIFSFLILPETKNKSILEILDSFN 472

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1213	NP_001246937.1	SP	42..482	CDD:273317	129/497 (26%)
CG1213	NP_001246937.1	MFS	47..460	CDD:119392	124/470 (26%)
slc2a11.2	NP_001339156.1	MFS	22..467	CDD:391944	127/480 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910