DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1213 and slc2a7

DIOPT Version :9

Sequence 1:	NP_001246937.1	Gene:	CG1213 / 40728	FlyBaseID:	FBgn0037387	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	NP_001120033.1	Gene:	slc2a7 / 100144999	XenbaseID:	XB-GENE-5811422	Length:	501	Species:	Xenopus tropicalis

Alignment Length:	499	Identity:	135/499 - (27%)
Similarity:	226/499 - (45%)	Gaps:	69/499 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 SPEPVKSGRIFMAAVAANL-SAFVVGTTLGWTSPIGPKLKSEDTSDSPLSRPITSDEDAW----- 91
            |..|:  .|:|:|..|..: .||..|..:...:....::: :..:::..||..::.|:.|
Frog    13 SRPPI--SRLFLAVCAVGIGGAFQYGYNVSIINAPTRQIQ-QFINNTWYSRHQSNLEEGWLTLIW 74

  Fly    92 --ISSLIAVGALVAPFVAGPMADRIGRKWVLLSSSLFFVLA---FGLNMVASEVWILYMSRLIQG 151
              |:|:..:|.|:...:.|.:||::|||..||.:::..:||   .|:...:....:|.:.|||.|
Frog    75 SVIASVFTLGGLLGTHIGGHLADKLGRKKTLLMNNVLAILAAFLMGIAYPSGCFELLIVGRLIIG 139

  Fly   152 FGVGFVMTVQPMYVGEISTDNVRGATGSLMQLFIVGGILYVYAIGPYVSYQAL-----QW----- 206
            ...|..:.|||:|:|||:..::||.|...|.:|:.|||.    .|..|..:.|     .|
Frog   140 INAGIGLCVQPLYLGEIAPRHIRGLTTVGMNIFLTGGIF----TGQLVGLRELFGGGDNWYFLLP 200

  Fly   207 -CCIVVPVVFDLV-FYMMPESP-YFFAGKGRKSEALKSLQFLRGQSAEGVHDEMAEIQANVEEAM 268
             |||  |.:..|. ....|||| |.......:.:..|:|:.|.|  :|....||.:|   ::|:.
Frog   201 TCCI--PAIIQLASLPWFPESPRYLLIENKDEYQCQKALKMLYG--SEHYQPEMDDI---LKESC 258

  Fly   269 ASKG----TVMDLFKNAGNRRALFICAGLISFQQLSGINVVLFNSQSIFASANTGLDPA------ 323
            |..|    |:..||.:...|..|.|.......|||||||.:.|.:..:|..|..   ||
Frog   259 ALNGEKPKTIFQLFSDRTVRWQLVIIILTNIGQQLSGINAIYFYAAYVFTKAGI---PANNIPYV 320

  Fly   324 -IATIIIGCVQVGSSALT-PLVADRLGRKVMLLTSSSVMSIGLAALGAFFYMQLVKGDISSVVWM 386
             :.|.:..|:    :||| .|:.|..||:::::...::|:.....|......|.|      ..|:
Frog   321 TLGTGLCECL----TALTCGLLIDIAGRRILIIGGYTLMAFWCTILTLTLTFQDV------YPWI 375

  Fly   387 PVPAL-IIYNIVYCTGFGP--LPWAVLGEMFPANIKSVASSVVASTCWTLGFLVTFFYPSL-DAL 447
            |..:: .::..:...|.||  :...:..|:|..:.:|.|..:..|..|...|.:...:|.| :.|
Frog   376 PYLSMSAVFAFILSFGLGPGGVTNTLTAELFTQSSRSAAFRISGSVGWITFFTIGMIFPFLVNGL 440

  Fly   448 GSYYAFWLFAVCMVVAFFFVLFVVMETKGLSLQQIQDRLNGKRN 491
            ..|...:.|..|::.| .|:.|:|.|||..|..:|:.... |||
Frog   441 NQYCFLFFFVECLLTA-SFIFFIVPETKNKSFLEIKKEFQ-KRN 482

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1213	NP_001246937.1	SP	42..482	CDD:273317	128/479 (27%)
CG1213	NP_001246937.1	MFS	47..460	CDD:119392	117/452 (26%)
slc2a7	NP_001120033.1	MFS_GLUT_Class2	23..474	CDD:340990	127/476 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910