DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1213 and slc2a5

DIOPT Version :9

Sequence 1:	NP_001246937.1	Gene:	CG1213 / 40728	FlyBaseID:	FBgn0037387	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	NP_001352581.1	Gene:	slc2a5 / 100006415	ZFINID:	ZDB-GENE-060222-2	Length:	511	Species:	Danio rerio

Alignment Length:	489	Identity:	130/489 - (26%)
Similarity:	223/489 - (45%)	Gaps:	54/489 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 KSGRIFMAAVAANL-----SAFVVGTTLGWTSPIGPKLKSEDTSDSPLSRPITSDEDAWIS---- 93
            :.|::.:...||:|     |:|..|..:...:...|:::.       ..|.|..|....:|
Zfish    12 RKGKVTLILAAASLVAGFGSSFQYGYNVAVVNSPAPEMQQ-------FYRRIYVDRYGPMSDNLL 69

  Fly    94 --------SLIAVGALVAPFVAGPMADRIGRKWVLLSSSLFFV---LAFGLNMVASEVWILYMSR 147
                    |:..:|......:..|:.::.|||..||.:::|.:   :..|::.||....|:.::|
Zfish    70 TLLWSVTVSMYPLGGFFGSLMVAPLVNKFGRKGTLLFNNIFSIVPAIMMGVSEVAGSFEIIIVAR 134

  Fly   148 LIQGFGVGFVMTVQPMYVGEISTDNVRGATGSLMQLFIVGGIL--YVYAIGPYVSYQALQWCCIV 210
            .:.|...|....|.|||:|||:..|.|||.|.:.||||..|||  .::.|...:..:. .|..::
Zfish   135 FLVGICAGLSSNVVPMYLGEIAPKNYRGAVGIVPQLFITVGILVAQIFGIRSILGNKE-GWPIML 198

  Fly   211 ----VPVVFDLVFY-MMPESP-YFFAGKGRKSEALKSLQFLRGQSAEGVHDEMAEIQANVEEAMA 269
                :|...:|:.. ..|||| |....||.:..|.|.||.|||  .|.|.:|:.|::.. |::..
Zfish   199 GLTGIPAAIELLLLPFFPESPRYMLIQKGDEKTARKGLQRLRG--CEDVDEELCEMRVE-EQSER 260

  Fly   270 SKG--TVMDLFKNAGNRRALFICAGLISFQQLSGINVVLFNSQSIFASANTGLDPA-IATIIIGC 331
            ::|  ::::||.....|..|.....:...|||||:|.:.:.:.||::||....|.. ..|:..|.
Zfish   261 AEGRLSLLNLFTFRSLRWQLLSVIFMNMGQQLSGVNAIYYYADSIYSSAGVSEDHVQYVTVGTGA 325

  Fly   332 VQVGSSALTPLVADRLGRKVMLLTSSSVMSIGLAALGAFFYMQLVKGDISSVVWMP---VPALII 393
            |.|..:.....:.::.|||::||....:.......|....|.|      :::.|:|   :..:|:
Zfish   326 VNVFMTITAVFIVEKSGRKLLLLIGFGICCAACVILTIALYFQ------TTLDWIPYVSIVCVIV 384

  Fly   394 YNIVYCTGFGPLPWAVLGEMFPANIKSVASSVVASTCWTLGFLVTFFYPSLD-ALGSYYAFWLFA 457
            |.|.:..|..|:|..:..|||..:.:..|..|..|..|...|.|...:|.|: .||. |:|.:||
Zfish   385 YVIGHAIGPSPIPTVITTEMFRQSSRPPAFMVAGSVHWLSNFTVGLVFPFLERGLGP-YSFIIFA 448

  Fly   458 VCMVVAFFFVLFVVMETKGLSLQQIQDRLNGKRN 491
            ...:....::..|:.|||..:..: ..:|..:||
Zfish   449 CICLATLIYIWIVIPETKNKTFLE-TSKLFAQRN 481

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1213	NP_001246937.1	SP	42..482	CDD:273317	126/474 (27%)
CG1213	NP_001246937.1	MFS	47..460	CDD:119392	122/447 (27%)
slc2a5	NP_001352581.1	Sugar_tr	23..477	CDD:306568	125/472 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100060
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.810