Protein Alignment CG1208 and ITR2

DIOPT Version :10

• Sequence 1: NP_001097692.1
• Gene: CG1208 / 40727
• FlyBaseID: FBgn0037386
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_014538.2
• Gene: ITR2 / 854050
• SGDID: S000005463
• Length: 609
• Species: Saccharomyces cerevisiae
• Alignment Length: 526
• Identity: 138/526 - (26%)
• Similarity: 230/526 - (43%)
• Gaps: 88/526 - (16%)

  Fly    17 VSQEDGDSRNPITYDLLQENQSKTSKTRQYVAAMIICLGAVAAGTALSWTSPVFPQISAGNESSF 81
            |:.|| |:...||:     |||        ::..||.|..||:.:..                .|
Yeast    89 VNDED-DTSVIITF-----NQS--------ISPFIITLTFVASISGF----------------MF 123

  Fly    82 NSTTGGISNSTSN-----ENDIRLTDSQKTLVGSMLPFGALFGALPSGYIADRIGRRYTAMVMDI 141
            ...||.||::..:     :|.: ||..:|.|:.:....|||..::.:|..||..|||...|..::
Yeast   124 GYDTGYISSALISINRDLDNKV-LTYGEKELITAATSLGALITSVGAGTAADVFGRRPCLMFSNL 187

  Fly   142 PFILAWITLSFANSVGWLYLGRFLIGIATGSFCVVAPMYISEIAETSIRGSLGTLFQLLLTIGIL 206
            .|::..|....|:....:..||.::|...|...:::|::|||||...|||.|..:..|.||.|.|
Yeast   188 MFLIGAILQITAHKFWQMAAGRLIMGFGVGIGSLISPLFISEIAPKMIRGRLTVINSLWLTGGQL 252

  Fly   207 FIYVVGALVS-----WKTLSLLCLIIPILLLVGLFIVPETPVYLLKNGKRSEANRALKWLWGDYC 266
            ..|..||.::     |:.|..|.||..:|.......:|:||.|.:..|....|...||   ..|.
Yeast   253 IAYGCGAGLNHVKNGWRILVGLSLIPTVLQFSFFCFLPDTPRYYVMKGDLKRAKMVLK---RSYV 314

  Fly   267 NTSNAIQAIQNDLDQTGVDAS------------------VKDLFSNRASRNGMVISVLLMVFQQF 313
            ||.:.|      :||...:.|                  ||:|.:..::...::|...|...|||
Yeast   315 NTEDEI------IDQKVEELSSLNQSIPGKNPITKFWNMVKELHTVPSNFRALIIGCGLQAIQQF 373

  Fly   314 SGINAVIFFMNEIFESSSTLNPNVCTIVVGVVQVIMTLASSLLIEKAGRKILLIFSSTIMTVCLA 378
            :|.|::::|...|||:....|.:..:|:|.....:.||.:...|:|.||:.:|:.....|||.|.
Yeast   374 TGWNSLMYFSGTIFETVGFKNSSAVSIIVSGTNFVFTLIAFFCIDKIGRRYILLIGLPGMTVALV 438

  Fly   379 M-------LG-AYNTINR--HTDLSQSIGWLPLLCIVLFIVSFSVGYGPIPWMMMGELFMPDVKG 433
            :       || .:|..:.  .:|...|.|.:.::.|:::...:::|.|.:|| ...|||..:|:|
Yeast   439 ICAIAFHFLGIKFNGADAVVASDGFSSWGIVIIVFIIVYAAFYALGIGTVPW-QQSELFPQNVRG 502

  Fly   434 IAVSLSVMMNW-----VCVSLVTWLFGVLNAGGADVPFWFFSAWMGVATAYVAIALQETKGKSAS 493
            :..|.:...||     :..:.:|.|..:...|    .|.||:....::|.:......|..|....
Yeast   503 VGTSYATATNWAGSLVIASTFLTMLQNITPTG----TFSFFAGVACLSTIFCYFCYPELSGLELE 563

  Fly   494 QIQSWL 499
            ::|:.|
Yeast   564 EVQTIL 569

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1208	NP_001097692.1	MFS_GLUT6_8_Class3_like	46..494	CDD:340916	127/490 (26%)
ITR2	NP_014538.2	MFS_HMIT_like	115..556	CDD:340918	122/471 (26%)