DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1208 and MAL11

DIOPT Version :9

Sequence 1:	NP_001097692.1	Gene:	CG1208 / 40727	FlyBaseID:	FBgn0037386	Length:	502	Species:	Drosophila melanogaster
Sequence 2:	NP_011805.3	Gene:	MAL11 / 853207	SGDID:	S000003521	Length:	616	Species:	Saccharomyces cerevisiae

Alignment Length:	549	Identity:	115/549 - (20%)
Similarity:	218/549 - (39%)	Gaps:	119/549 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 VSQEDGDSRNPI-----TYDLLQENQSKTSKTRQ--------------YVAAMIICLGAVAAGTA 62
            :...|.|:.|.|     |.|..:.|..:.|.|.:              .|:..::..|...|..:
Yeast    64 LGDSDEDNENVINEMNATDDANEANSEEKSMTLKQALLKYPKAALWSILVSTTLVMEGYDTALLS 128

  Fly    63 LSWTSPVFPQISAGNESSFNSTTGGISNSTSNENDIRLTDSQKTLVGSMLPFGALFGALPSGYIA 127
            ..:..|||       :..|.:..|        |....:|...:..:...:..|.:.|...:.|:.
Yeast   129 ALYALPVF-------QRKFGTLNG--------EGSYEITSQWQIGLNMCVLCGEMIGLQITTYMV 178

  Fly   128 DRIGRRYTAMVMDIPFILAWI-TLSFANSVGWLYLGRFLIGIATGSFCVVAPMYISEIAETSIR- 190
            :.:|.||| |:..:..:.|:| .|.:..|:..:.:|:.|..|..|.|..:|..|.||:...::|
Yeast   179 EFMGNRYT-MITALGLLTAYIFILYYCKSLAMIAVGQILSAIPWGCFQSLAVTYASEVCPLALRY 242

  Fly   191 -----GSLGTLFQLLLTIGIL-----------FIYVVGALVSWKTLSLLCLIIPILLLVGLFIVP 239
                 .::..||..:...||:           ..|.:...:.|        |.|..|::|:|..|
Yeast   243 YMTSYSNICWLFGQIFASGIMKNSQENLGNSDLGYKLPFALQW--------IWPAPLMIGIFFAP 299

  Fly   240 ETPVYLLKNGKRSEANRALKWLWGDYCNTSNAIQAIQNDLDQTGVDASVKDLFSNR--ASRNGMV 302
            |:|.:|::..:.:||.::|..:    .:...|.:.||.||....::.:::   ..|  ||::|
Yeast   300 ESPWWLVRKDRVAEARKSLSRI----LSGKGAEKDIQVDLTLKQIELTIE---KERLLASKSG-- 355

  Fly   303 ISVLLMVFQQFSGIN------------------AVIF-FMNEIFESSSTLNPNVCTIVVGVVQVI 348
                 ..|..|.|:|                  ||:. :....||.:........|.  .::|..
Yeast   356 -----SFFNCFKGVNGRRTRLACLTWVAQNSSGAVLLGYSTYFFERAGMATDKAFTF--SLIQYC 413

  Fly   349 M----TLASSLLIEKAGRKILLIFSSTIMTVCLAMLGAYNTINRHTDLSQSIGWLPLLCIVLFIV 409
            :    ||.|.::..:.||..:|.:......|||.::|... ....:..|...|.| ||.:..|
Yeast   414 LGLAGTLCSWVISGRVGRWTILTYGLAFQMVCLFIIGGMG-FGSGSSASNGAGGL-LLALSFF-- 474

  Fly   410 SFSVGYGPIPWMMMGELFMPDVKGIAVSLSVMMNWVCVSLVTWLFGVLNAGGADVPFWFFSA--- 471
             ::.|.|.:.:.::.|:...:::    :.::::..:|.:|:..:..:|.....:|..|.:.|
Yeast   475 -YNAGIGAVVYCIVAEIPSAELR----TKTIVLARICYNLMAVINAILTPYMLNVSDWNWGAKTG 534

  Fly   472 --WMG---VATAYVAIALQETKGKSASQI 495
              |.|   |..|:|.|.|.||.|::.|:|
Yeast   535 LYWGGFTAVTLAWVIIDLPETTGRTFSEI 563

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1208	NP_001097692.1	MFS	96..482	CDD:119392	90/436 (21%)
CG1208	NP_001097692.1	MFS_1	96..443	CDD:284993	79/389 (20%)
MAL11	NP_011805.3	SP	81..563	CDD:273317	110/530 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342803
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.830