Protein Alignment CG1208 and Slc2a8

DIOPT Version :10

• Sequence 1: NP_001097692.1
• Gene: CG1208 / 40727
• FlyBaseID: FBgn0037386
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_445946.2
• Gene: Slc2a8 / 85256
• RGDID: 620611
• Length: 478
• Species: Rattus norvegicus
• Alignment Length: 512
• Identity: 156/512 - (30%)
• Similarity: 260/512 - (50%)
• Gaps: 60/512 - (11%)

  Fly    17 VSQEDGDSRNPITYDLLQENQSKTSKTRQYVAAMIICLGAVAAGTALSWTSPVFPQISAGNESSF 81
            :|.||.....|:   |...........|.::|.....||.::.|.||.::||..|.:......:
  Rat     1 MSPEDPQETQPL---LRSPGARAPGGRRVFLATFAAALGPLSFGFALGYSSPAIPSLRRTAPPA- 61

  Fly    82 NSTTGGISNSTSNENDIRLTDSQKTLVGSMLPFGALFGALPSGYIADRIGRRYTAMVMDIPFILA 146
                            :||.|:..:..|:::..||..|.:..|::.||.||:.:.::..:||:..
  Rat    62 ----------------LRLGDTAASWFGAVVTLGAAAGGVLGGWLLDRAGRKLSLLLCTVPFVTG 110

  Fly   147 WITLSFANSVGWLYLGRFLIGIATGSFCVVAPMYISEIAETSIRGSLGTLFQLLLTIGILFIYVV 211
            :..::.|..|..|..||.|.|:|.|...:|||:||||||..::||.||:..||::..|||..||.
  Rat   111 FAVITAARDVWMLLGGRLLTGLACGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVTGILLAYVA 175

  Fly   212 GALVSWKTLSLLCLIIPILLLVGLFIVPETPVYLLKNGKRSEANRALKWLWGDYCNTSNAIQAIQ 276
            |.::.|:.|::|..:.|.|:|:.:..:||||.:||...:..||..||::|||.           :
  Rat   176 GWVLEWRWLAVLGCVPPTLMLLLMCYMPETPRFLLTQHQYQEAMAALRFLWGS-----------E 229

  Fly   277 NDLDQTGVDASVKDLFSNRASRNG----MVISVLLMVFQQFSGINAVIFFMNEIFESSSTLNPNV 337
            ...::..|.|..:........|.|    ::|.:.||||||.||:||::|:.|.|||.:...:.::
  Rat   230 EGWEEPPVGAEHQGFQLAMLRRPGVHKPLIIGICLMVFQQLSGVNAIMFYANTIFEEAKFKDSSL 294

  Fly   338 CTIVVGVVQVIMTLASSLLIEKAGRKILLIFSSTIMTVCLAMLGAYNTINRH------------- 389
            .::.||::||:.|..::|::::||||:||..|..||...::..|.|..:.:.
  Rat   295 ASVTVGIIQVLFTAVAALIMDRAGRKLLLALSGVIMVFSMSAFGTYFKLTQSGPSNSSHVGLLVP 359

  Fly   390 -----TDLSQSIGWLPLLCIVLFIVSFSVGYGPIPWMMMGELFMPDVKGIAVSLSVMMNWVCVSL 449
                 .|:...:.||.:..:.|||..|:||:|||||::|.|:|...:||:|..:.|:.||....|
  Rat   360 ISAEPADVHLGLAWLAVGSMCLFIAGFAVGWGPIPWLLMSEIFPLHIKGVATGVCVLTNWFMAFL 424

  Fly   450 VTWLFG----VLNAGGADVPFWFFSAWMGVATAYVAIALQETKGKSASQIQSWLSGR 502
            ||..|.    :|...||   ||..:|:..::..:....:.||||::..||.:...||
  Rat   425 VTKEFNSIMEILRPYGA---FWLTAAFCILSVLFTLTFVPETKGRTLEQITAHFEGR 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1208	NP_001097692.1	MFS_GLUT6_8_Class3_like	46..494	CDD:340916	146/473 (31%)
Slc2a8	NP_445946.2	Dileucine internalization motif. /evidence=ECO:0000269|PubMed:10671487	12..13		0/3 (0%)
		MFS	27..470	CDD:475125	146/473 (31%)