Protein Alignment CG1208 and MPH2

DIOPT Version :10

• Sequence 1: NP_001097692.1
• Gene: CG1208 / 40727
• FlyBaseID: FBgn0037386
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_010034.1
• Gene: MPH2 / 851350
• SGDID: S000002406
• Length: 609
• Species: Saccharomyces cerevisiae
• Alignment Length: 538
• Identity: 125/538 - (23%)
• Similarity: 211/538 - (39%)
• Gaps: 85/538 - (15%)

  Fly     2 DSEKVVRAMARWWQTVSQEDGDSRN-PITYDLLQENQSKTSKTRQYVAAMIICLGAVAAGTALSW 65
            ||.||:..:....:...:.|...|. |:...|  ....|.:.....|:..:|..|...|.....:
Yeast    60 DSNKVITEIFDATEDAKEADESERGMPLATAL--NTYPKAAAWSLLVSTTLIMEGYDTAILGAFY 122

  Fly    66 TSPVFPQISAGNESSFNSTTGGISNSTSNENDIRLTDSQKTLVGSMLPFGALFGALPSGYIADRI 130
            ..|:| |...|::   |..||....|.|.:..:.|......:||..|          :|...|.:
Yeast   123 ALPIF-QRKFGSQ---NDKTGEWEISASWQIGLTLCYMAGEIVGLQL----------TGPSVDLV 173

  Fly   131 GRRYTAMVMDIPFILAWIT--LSFANSVGWLYLGRFLIGIATGSFCVVAPMYISEIAETSIRGSL 193
            |.|||.::  ..|.||..|  |.|.||:|.:.:|:.|.|:..|.|..:...|.|||...::|..|
Yeast   174 GNRYTLII--ALFFLAAFTFILYFCNSLGMIAVGQALCGMPWGCFQCLTVSYASEICPLALRYYL 236

  Fly   194 GTLFQLLLTIGILFIYVVGAL-----------VSWKTLSLLCLIIPILLLVGLFIVPETPVYLLK 247
            .|...|....|.||  ..|.:           :.:|....|..|:|:.|.:|:|..||:|.:|:|
Yeast   237 TTYSNLCWLFGQLF--AAGIMKNSQKKYADSELGYKLPFALQWILPVPLALGIFFAPESPWWLVK 299

  Fly   248 NGKRSEANRALKWLWGDYCNTSNAIQAIQND-----LDQ----TGVDASVKDLFSNRASRNGMVI 303
            .|:..||.|:|:............:..::.|     :|:    |..:.|..|.|.::.:|....|
Yeast   300 KGRFDEARRSLRRTLSGKGPEKEILVTLEVDKIKVTIDKEKRLTSKEGSYSDCFEDKINRRRTRI 364

  Fly   304 SVLLMVFQQFSGINAVIFFMNEIFESSSTLNPNVCTIVVGVVQVIMTLASSLLIEKA----GRKI 364
            :.|....|...| :.:|.:....:|.:..  ....:....::|..:.:.::.|...|    ||..
Yeast   365 TCLCWAGQATCG-SILIGYSTYFYEKAGV--STEMSFTFSIIQYCLGICATFLSWWASKYFGRYD 426

  Fly   365 LLIFSSTIMTVCLAMLGAYNTINRHTDLSQSIGWLPLLCIVLFIVSFSVGYGPIPWMMMGELFMP 429
            |..|.....|:...::|.....:.|   ...:|...||..|.|.  :::|..|:.:.::.|  ||
Yeast   427 LYAFGLAFQTIVFFIIGGLGCSSTH---GSKMGSGSLLMAVAFF--YNLGIAPVVFCLVSE--MP 484

  Fly   430 D----VKGIAVSLSV--MMNWVCVSLV-------TWLFGVLNAGGADVPFWFFSAWMGV----AT 477
            .    .|.|.::.:.  :::.:|..|:       .|     |.|.....||      ||    ..
Yeast   485 SSRLRTKTIILARNTYNVVSIICSVLILYQLNSKKW-----NWGAKSGFFW------GVLCFCTL 538

  Fly   478 AYVAIALQETKGKSASQI 495
            .:..:.|.||.||:..:|
Yeast   539 IWAVVDLPETAGKTFVEI 556

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1208	NP_001097692.1	MFS_GLUT6_8_Class3_like	46..494	CDD:340916	115/490 (23%)
MPH2	NP_010034.1	SP	72..556	CDD:273317	120/524 (23%)