DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1208 and GEX1

DIOPT Version :9

Sequence 1:	NP_001097692.1	Gene:	CG1208 / 40727	FlyBaseID:	FBgn0037386	Length:	502	Species:	Drosophila melanogaster
Sequence 2:	NP_009863.2	Gene:	GEX1 / 850289	SGDID:	S000000575	Length:	615	Species:	Saccharomyces cerevisiae

Alignment Length:	402	Identity:	69/402 - (17%)
Similarity:	135/402 - (33%)	Gaps:	151/402 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 NPITYDL------LQENQSKTSK--TRQYVAAMIICLGAVAAGTALSWTSPVFPQISAGNESSFN 82
            |..||.:      |:||:..:::  :.:|...:|........|.:|.:|              ..
Yeast    30 NDDTYSMTSTFFKLKENEIMSAQFDSLKYKILLISTAFVCGFGISLDYT--------------LR 80

  Fly    83 STTGGISNSTSNENDIRLT---DSQKTLVGSMLPFGALFGALPSGYIADRIGRRYTAMVMDIPFI 144
            ||..|.:.::.:|:.:..|   .:....|||.:.:..|         :|..||....:|..|.:|
Yeast    81 STYTGYATNSYSEHSLLSTVQVINAVVSVGSQVVYSRL---------SDHFGRLRLFLVATIFYI 136

  Fly   145 LAWITLSFANSVGWLYLGRFLIGIATGSF---CVVAPMYISEIAETSIRGSLGTLFQLLLTI--- 203
            :..|..|.|..         |...|.||.   |                |.:||  .||||:
Yeast   137 MGTIIQSQATR---------LTMYAAGSVFYNC----------------GYVGT--NLLLTLILS 174

  Fly   204 ------------------GILFIYVVGALV---------SWKTLSLLCLIIPILLLVGLFIVPET 241
                              .|:..::.|.::         || .:::...|.|:..|..:|::
Yeast   175 DFSSLKWRMFYQYASYWPYIIIPWISGNIITAANPQKNWSW-NIAMWAFIYPLSALPIIFLI--- 235

  Fly   242 PVYLLKNGKRSEANRALKWLWGDYCNTSNAIQAIQNDLDQTGVDASVKDLFSNRASRNGMVISVL 306
             :|:     :.::::..:|                         .|:|:  ..|..|.|.:...|
Yeast   236 -LYM-----KYKSSKTAEW-------------------------RSLKE--QARKERTGGLFENL 267

  Fly   307 LMVFQQFSGINAVIFFMNEIFESSSTLNPNVCTIVVGVVQVIMTLASSLLIEKAGRKILLIFSST 371
            :.:|.:...:..::.                 |:.:|.:.|.:|||:....:....||:   ::.
Yeast   268 VFLFWKLDIVGILLI-----------------TVSLGCILVPLTLANETSQKWHNSKII---ATL 312

  Fly   372 IMTVCLAMLGAY 383
            :...||..:..|
Yeast   313 VSGGCLFFIFLY 324

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1208	NP_001097692.1	MFS	96..482	CDD:119392	54/324 (17%)
CG1208	NP_001097692.1	MFS_1	96..443	CDD:284993	54/324 (17%)
GEX1	NP_009863.2	MFS_ARN_like	59..571	CDD:340880	62/373 (17%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900