DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1208 and INT2

DIOPT Version :9

Sequence 1:	NP_001097692.1	Gene:	CG1208 / 40727	FlyBaseID:	FBgn0037386	Length:	502	Species:	Drosophila melanogaster
Sequence 2:	NP_174313.1	Gene:	INT2 / 839902	AraportID:	AT1G30220	Length:	580	Species:	Arabidopsis thaliana

Alignment Length:	542	Identity:	129/542 - (23%)
Similarity:	224/542 - (41%)	Gaps:	103/542 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 ALSWTSPVFPQI--SAG-NESSFNSTTGGISNSTSN-ENDIRLTDSQ---KTLVGSMLPFGALFG 119
            :|:|.:|...::  ||| ....|...||.||.:... .:|.:..|..   :.::.||...||:.|
plant    20 SLTWKNPYVLRLAFSAGIGGLLFGYDTGVISGALLYIRDDFKSVDRNTWLQEMIVSMAVAGAIVG 84

  Fly   120 ALPSGYIADRIGRRYTAMVMDIPFILAWITLSFANSVGWLYLGRFLIGIATGSFCVVAPMYISEI 184
            |...|:..|::|||...::.|..|:|..|.::.|.:...|.:||..:|:..|...:.||:||||.
plant    85 AAIGGWANDKLGRRSAILMADFLFLLGAIIMAAAPNPSLLVVGRVFVGLGVGMASMTAPLYISEA 149

  Fly   185 AETSIRGSLGTLFQLLLTIGILFIYVVGALV-----SWKTLSLLCLIIPILLLVGLFIVPETPVY 244
            :...|||:|.:....|:|.|....|::....     :|:.:..:..|..:|..|.:|.:||:|.:
plant   150 SPAKIRGALVSTNGFLITGGQFLSYLINLAFTDVTGTWRWMLGIAGIPALLQFVLMFTLPESPRW 214

  Fly   245 LLKNGKRSEANRALKWLWG--DYCNTSNAIQ-AIQNDLDQTGVDASVK--DLFSNRASRNGMVIS 304
            |.:.|:..||...|:.::.  |......|:: :::.::.:.|....:.  .|...:..|.|::..
plant   215 LYRKGREEEAKAILRRIYSAEDVEQEIRALKDSVETEILEEGSSEKINMIKLCKAKTVRRGLIAG 279

  Fly   305 VLLMVFQQFSGINAVIFFMNEI-----FESSSTLNPNVCTIVVGVVQVIMTLASSLLIEKAGRKI 364
            |.|.|||||.|||.|:::...|     |.|:.|  ..:.::|...:....::.|...|::.|||.
plant   280 VGLQVFQQFVGINTVMYYSPTIVQLAGFASNRT--ALLLSLVTAGLNAFGSIISIYFIDRIGRKK 342

  Fly   365 LLIFSSTIMTVCLAML-GAYNTINRHTDLSQSI-------------------------------- 396
            |||.|...:.:.|.:| |.:.....|.....|:
plant   343 LLIISLFGVIISLGILTGVFYEAATHAPAISSLETQRFNNISCPDYKSAMNTNAWDCMTCLKASS 407

  Fly   397 ---------------------------------------------GWLPLLCIVLFIVSFSVGYG 416
                                                         ||..||.:.|:|:.||.|.|
plant   408 PSCGYCSSPIGKEHPGACWISDDSVKDLCHNENRLWYTRGCPSNFGWFALLGLGLYIIFFSPGMG 472

  Fly   417 PIPWMMMGELFMPDVKGIAVSLSVMMNWVCVSLVTWLF-GVLNAGGADVPFWFFSAWMGVATAYV 480
            .:||::..|::....:||...::...||:...:|...| .:..|.|....|..|.....:|..:|
plant   473 TVPWIVNSEIYPLRFRGICGGIAATANWISNLIVAQSFLSLTEAIGTSWTFLIFGVISVIALLFV 537

  Fly   481 AIALQETKGKSASQIQSWLSGR 502
            .:.:.||||....:|:..|..|
plant   538 MVCVPETKGMPMEEIEKMLERR 559

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1208	NP_001097692.1	MFS	96..482	CDD:119392	111/482 (23%)
CG1208	NP_001097692.1	MFS_1	96..443	CDD:284993	101/442 (23%)
INT2	NP_174313.1	SP	25..552	CDD:273317	124/528 (23%)
INT2	NP_174313.1	MFS	33..541	CDD:119392	119/509 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X729
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810