DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1208 and ESL1

DIOPT Version :9

Sequence 1:	NP_001097692.1	Gene:	CG1208 / 40727	FlyBaseID:	FBgn0037386	Length:	502	Species:	Drosophila melanogaster
Sequence 2:	NP_849618.1	Gene:	ESL1 / 837413	AraportID:	AT1G08920	Length:	477	Species:	Arabidopsis thaliana

Alignment Length:	507	Identity:	147/507 - (28%)
Similarity:	249/507 - (49%)	Gaps:	57/507 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 TVSQEDGDSRNPITYDLLQENQSKTSKTRQYVAAMI-------ICLGAVAAGTALSWTSPVFPQI 73
            |:|:   :|||.....||::||:..::.|  :.|::       :| |:...|.|..::|.
plant     2 TMSE---NSRNLEAGLLLRKNQNDINECR--ITAVVLFSTFVSVC-GSFCFGCAAGYSSV----- 55

  Fly    74 SAGNESSFNSTTGGISNSTSNENDIRLTDSQKTLVGSMLPFGALFGALPSGYIADRIGRRYTAMV 138
                     :.||.|       ||:.|:.:|.::.||::.||.:.||:.||.:||.:||:.|...
plant    56 ---------AQTGII-------NDLGLSVAQYSMFGSIMTFGGMIGAIFSGKVADLMGRKGTMWF 104

  Fly   139 MDIPFILAWITLSFANSVGWLYLGRFLIGIATGSFCVVAPMYISEIAETSIRGSLGTLFQLLLTI 203
            ..|..|..|:.::.|....||.:||...|.|.|....|.|:||:||....:||:.....||:.:.
plant   105 AQIFCIFGWVAVALAKDSMWLDIGRLSTGFAVGLLSYVIPVYIAEITPKHVRGAFVFANQLMQSC 169

  Fly   204 GILFIYVVGALVSWKTLSLLCLIIPILLLVGLFIVPETPVYLLKNGKRSEANRALKWLWGDYCNT 268
            |:...||:|..|.|:.|:|:.||...|.:|.||.:||:|..|.|.|...|...:|:.|.||..:.
plant   170 GLSLFYVIGNFVHWRNLALIGLIPCALQVVTLFFIPESPRLLGKWGHEKECRASLQSLRGDDADI 234

  Fly   269 SNAIQAIQND--LDQTGVDASVKDLFSNRASRNGMVISVLLMVFQQFSGINAVIFFMNEIFESSS 331
            |.....|:..  |...|..:.|.|||..|.:.: :||.|.||:.||.||.:.:::::..:|:...
plant   235 SEEANTIKETMILFDEGPKSRVMDLFQRRYAPS-VVIGVGLMLLQQLSGSSGLMYYVGSVFDKGG 298

  Fly   332 TLNPNVCTIVVGVVQVIMTLASSLLIEKAGRKILLIFSSTIMT-----VCLAML--------GAY 383
             ...::.::::.|:.:...|...:|:||.||:.||:.:...:.     :|...|        .:|
plant   299 -FPSSIGSMILAVIMIPKALLGLILVEKMGRRPLLLMNDLYLQASTGGMCFFSLLLSFSFCFRSY 362

  Fly   384 NTINRHTDLSQSIGWLPLLCIVLFIVSFSVGYGPIPWMMMGELFMPDVKGIAVSLSVMMNWVCVS 448
            ..::..|.:...||      :|.||.||:||.|.:||::|.|:|..:||..|.:|..:.||....
plant   363 GMLDELTPIFTCIG------VVGFISSFAVGMGGLPWIIMSEIFPMNVKVSAGTLVTLANWSFGW 421

  Fly   449 LVTWLFGVLNAGGADVPFWFFSAWMGVATAYVAIALQETKGKSASQIQSWLS 500
            :|.:.:..:....|...|..|....|....::...:.||||::...||:.|:
plant   422 IVAFAYNFMLEWNASGTFLIFFTICGAGIVFIYAMVPETKGRTLEDIQASLT 473

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1208	NP_001097692.1	MFS	96..482	CDD:119392	121/400 (30%)
CG1208	NP_001097692.1	MFS_1	96..443	CDD:284993	114/361 (32%)
ESL1	NP_849618.1	Sugar_tr	36..469	CDD:278511	133/462 (29%)
ESL1	NP_849618.1	MFS	36..457	CDD:119392	129/450 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	1	1.000	-	-		FOG0000275
OrthoInspector	1	1.000	-	-		otm2619
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48021
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.920