DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1208 and INT3

DIOPT Version :9

Sequence 1:	NP_001097692.1	Gene:	CG1208 / 40727	FlyBaseID:	FBgn0037386	Length:	502	Species:	Drosophila melanogaster
Sequence 2:	NP_181117.1	Gene:	INT3 / 818146	AraportID:	AT2G35740	Length:	580	Species:	Arabidopsis thaliana

Alignment Length:	545	Identity:	116/545 - (21%)
Similarity:	233/545 - (42%)	Gaps:	110/545 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    64 SWTSPVFPQ--ISAG-NESSFNSTTGGISNSTSN-ENDIRLTDSQ---KTLVGSMLPFGALFGAL 121
            :|.:|...:  :||| ....|...||.|:.:... :.:....|::   :.::.||...||:.||.
plant    20 TWETPYIMRLALSAGIGGLLFGYNTGVIAGALLYIKEEFGEVDNKTWLQEIIVSMTVAGAIVGAA 84

  Fly   122 PSGYIADRIGRRYTAMVMDIPFILAWITLSFANSVGWLYLGRFLIGIATGSFCVVAPMYISEIAE 186
            ..|:..|:.|||.:.::.|:.|:|..:.:..|::...:.|||.|:|...|...:.:|:||||::.
plant    85 IGGWYNDKFGRRMSVLIADVLFLLGALVMVIAHAPWVIILGRLLVGFGVGMASMTSPLYISEMSP 149

  Fly   187 TSIRGSLGTLFQLLLT--------IGILFIYVVGALVSWKTLSLLCLIIPILLLVGLFIVPETPV 243
            ..|||:|.:...||:|        |.:.|::..|   :|:.:..:..|..|:....:..:||:|.
plant   150 ARIRGALVSTNGLLITGGQFLSYLINLAFVHTPG---TWRWMLGVSAIPAIIQFCLMLTLPESPR 211

  Fly   244 YLLKNGKRSEANRALKWLW------GDYCNTSNAIQAIQNDLDQTGVDAS--VKDLFSNRASRNG 300
            :|.:|.:::|:...|:.::      .:......:::|...|.|..|...|  ::...||...|:|
plant   212 WLYRNDRKAESRDILERIYPAEMVEAEIAALKESVRAETADEDIIGHTFSDKLRGALSNPVVRHG 276

  Fly   301 MVISVLLMVFQQFSGINAVIFFMNEIFE---SSSTLNPNVCTIVVGVVQVIMTLASSLLIEKAGR 362
            :...:.:.|.|||.|||.|:::...|.:   .:|........::...:..:.::.|.:.:::.||
plant   277 LAAGITVQVAQQFVGINTVMYYSPTILQFAGYASNKTAMALALITSGLNAVGSVVSMMFVDRYGR 341

  Fly   363 KILLIFSSTIMTVCLAMLGA-YNTINRH------------------------------------- 389
            :.|:|.|...:..||.:|.| :|..:.|
plant   342 RKLMIISMFGIITCLVILAAVFNEASNHAPKIDKRDSRNFAKNATCPAFAPFTASRSPPSNWNCM 406

  Fly   390 --------------------------TDLS----------------QSIGWLPLLCIVLFIVSFS 412
                                      .|:.                ...|:|.::.:.|:|:.::
plant   407 KCLQYDCGFCSNGAQEYAPGACIVQSADMKALCHSKGRTFFKDGCPSKFGYLAIVFLGLYIIVYA 471

  Fly   413 VGYGPIPWMMMGELFMPDVKGIAVSLSVMMNWVCVSLVTWLFGVL-NAGGADVPFWFFSAWMGVA 476
            .|.|.:||::..|::....:|:|..::.:.||:...:|:..|..| ||.|:...|..|:....|.
plant   472 PGMGTVPWIVNSEIYPLRYRGLAGGIAAVSNWMSNLVVSETFLTLTNAVGSSGTFLLFAGSSAVG 536

  Fly   477 TAYVAIALQETKGKSASQIQSWLSG 501
            ..::.:.:.||||....:::..|.|
plant   537 LFFIWLLVPETKGLQFEEVEKLLEG 561

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1208	NP_001097692.1	MFS	96..482	CDD:119392	101/488 (21%)
CG1208	NP_001097692.1	MFS_1	96..443	CDD:284993	90/448 (20%)
INT3	NP_181117.1	SP	1..555	CDD:273317	114/537 (21%)
INT3	NP_181117.1	MFS	31..>364	CDD:119392	83/335 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X729
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810