Protein Alignment CG1208 and SLC2A5

DIOPT Version :10

• Sequence 1: NP_001097692.1
• Gene: CG1208 / 40727
• FlyBaseID: FBgn0037386
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_003030.1
• Gene: SLC2A5 / 6518
• HGNCID: 11010
• Length: 501
• Species: Homo sapiens
• Alignment Length: 484
• Identity: 126/484 - (26%)
• Similarity: 226/484 - (46%)
• Gaps: 37/484 - (7%)

  Fly    35 ENQSKTSKTRQYVAAMIICLGAVAAGTALSW-------TSPVFPQISAGNESSFNSTTGGISNST 92
            |.|.::.|..:....:.:.....|.|::..:       .||........||:.:..|...:
Human     2 EQQDQSMKEGRLTLVLALATLIAAFGSSFQYGYNVAAVNSPALLMQQFYNETYYGRTGEFM---- 62

  Fly    93 SNENDIRLTDSQKTLVGSMLPFGALFGALPSGYIADRIGRRYTAMVMDIPFILAWITLS---FAN 154
               .|..||......| ||.|||...|:|..|.:.::.||:...:..:|..|:..|.:.   .|.
Human    63 ---EDFPLTLLWSVTV-SMFPFGGFIGSLLVGPLVNKFGRKGALLFNNIFSIVPAILMGCSRVAT 123

  Fly   155 SVGWLYLGRFLIGIATGSFCVVAPMYISEIAETSIRGSLGTLFQLLLTIGILFIYVVGA------ 213
            |...:.:.|.|:||..|....|.|||:.|:|..::||:||.:.||.:|:|||...:.|.
Human   124 SFELIIISRLLVGICAGVSSNVVPMYLGELAPKNLRGALGVVPQLFITVGILVAQIFGLRNLLAN 188

  Fly   214 LVSWKTLSLLCLIIPILLLVGLFIVPETPVYLLKNGK-RSEANRALKWLWG-DYCNTSNAIQAIQ 276
            :..|..|..|..:...|.|:.|...||:|.|||...| .:.|.:||:.|.| |..:...|....:
Human   189 VDGWPILLGLTGVPAALQLLLLPFFPESPRYLLIQKKDEAAAKKALQTLRGWDSVDREVAEIRQE 253

  Fly   277 NDLDQTGVDASVKDLFSNRASRNGMVISVLLMVFQQFSGINAVIFFMNEIFESSSTLNPNV--CT 339
            ::.::.....||..||..|:.|..::..::||..||.||:||:.::.::|:.|:.....:|  .|
Human   254 DEAEKAAGFISVLKLFRMRSLRWQLLSIIVLMGGQQLSGVNAIYYYADQIYLSAGVPEEHVQYVT 318

  Fly   340 IVVGVVQVIMTLASSLLIEKAGRKILLIFSSTIMTVCLAMLGAYNTINRHTDLSQSIGWLP---L 401
            ...|.|.|:||..:..::|..||::||:...:|..:...:|.|      ...|..::.|:|   :
Human   319 AGTGAVNVVMTFCAVFVVELLGRRLLLLLGFSICLIACCVLTA------ALALQDTVSWMPYISI 377

  Fly   402 LCIVLFIVSFSVGYGPIPWMMMGELFMPDVKGIAVSLSVMMNWVCVSLVTWLFGVLNAGGADVPF 466
            :|::.:::..::|..|||.:::.|:|:...:..|..:...::|:....|..:|..:..|.....|
Human   378 VCVISYVIGHALGPSPIPALLITEIFLQSSRPSAFMVGGSVHWLSNFTVGLIFPFIQEGLGPYSF 442

  Fly   467 WFFSAWMGVATAYVAIALQETKGKSASQI 495
            ..|:....:.|.|:.:.:.|||.|:..:|
Human   443 IVFAVICLLTTIYIFLIVPETKAKTFIEI 471

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1208	NP_001097692.1	MFS_GLUT6_8_Class3_like	46..494	CDD:340916	122/470 (26%)
SLC2A5	NP_003030.1	MFS_GLUT_Class2	23..471	CDD:340990	122/461 (26%)