Protein Alignment CG1208 and SLC2A2

DIOPT Version :10

• Sequence 1: NP_001097692.1
• Gene: CG1208 / 40727
• FlyBaseID: FBgn0037386
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_000331.1
• Gene: SLC2A2 / 6514
• HGNCID: 11006
• Length: 524
• Species: Homo sapiens
• Alignment Length: 406
• Identity: 127/406 - (31%)
• Similarity: 210/406 - (51%)
• Gaps: 34/406 - (8%)

  Fly   108 VGSMLPFGALFGALPSGYIADRIGRRYTAMVMDIPFILAWITLSFAN---SVGWLYLGRFLIGIA 169
            ||.|.  .:.||    |::.|.:||....:|.:|..::..:.:.|:.   |...:..||.:.|:.
Human   106 VGGMT--ASFFG----GWLGDTLGRIKAMLVANILSLVGALLMGFSKLGPSHILIIAGRSISGLY 164

  Fly   170 TGSFCVVAPMYISEIAETSIRGSLGTLFQLLLTIGILFI------YVVGALVSWKTLSLLCLIIP 228
            .|....:.||||.|||.|::||:|||..||.:..|||..      :::|....|..|..|..:..
Human   165 CGLISGLVPMYIGEIAPTALRGALGTFHQLAIVTGILISQIIGLEFILGNYDLWHILLGLSGVRA 229

  Fly   229 ILLLVGLFIVPETPVYL-LKNGKRSEANRALKWLWGDYCNTSNAIQAIQNDLDQTGVD--ASVKD 290
            ||..:.||..||:|.|| :|..:..:|.::||.|.| |.:.:..|..::.:.::...:  .|:..
Human   230 ILQSLLLFFCPESPRYLYIKLDEEVKAKQSLKRLRG-YDDVTKDINEMRKEREEASSEQKVSIIQ 293

  Fly   291 LFSNRASRNGMVISVLLMVFQQFSGINAVIFFMNEIFESSSTLNPNVCTIVVGVVQVIMTLASSL 355
            ||:|.:.|..::::::|.|.|||||||.:.::...||:::....|...||.||.|.::.|..|..
Human   294 LFTNSSYRQPILVALMLHVAQQFSGINGIFYYSTSIFQTAGISKPVYATIGVGAVNMVFTAVSVF 358

  Fly   356 LIEKAGRKILLIFSSTIMTVC-LAMLGAYNTINRHTDLSQSIGWLPLLCIVLFIVSFSVGYGPIP 419
            |:|||||:.|.:...:.|.|| :.|......:|:.:.:|    ::.::.|.||:..|.:|.||||
Human   359 LVEKAGRRSLFLIGMSGMFVCAIFMSVGLVLLNKFSWMS----YVSMIAIFLFVSFFEIGPGPIP 419

  Fly   420 WMMMGELFMPDVKGIAVSLSVMMNWVCVSLVTWLFGVLNAGGADV--PFWFFSAWMGVATAYVAI 482
            |.|:.|.|....:..|::::...||.|..:|...|..:    ||.  |:.|| .:.||..|:...
Human   420 WFMVAEFFSQGPRPAALAIAAFSNWTCNFIVALCFQYI----ADFCGPYVFF-LFAGVLLAFTLF 479

  Fly   483 A---LQETKGKSASQI 495
            .   :.||||||..:|
Human   480 TFFKVPETKGKSFEEI 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1208	NP_001097692.1	MFS_GLUT6_8_Class3_like	46..494	CDD:340916	126/403 (31%)
SLC2A2	NP_000331.1	MFS_GLUT_Class1	12..490	CDD:340989	123/399 (31%)