DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1208 and slc2a5

DIOPT Version :9

Sequence 1:	NP_001097692.1	Gene:	CG1208 / 40727	FlyBaseID:	FBgn0037386	Length:	502	Species:	Drosophila melanogaster
Sequence 2:	NP_001008187.1	Gene:	slc2a5 / 493549	XenbaseID:	XB-GENE-494009	Length:	517	Species:	Xenopus tropicalis

Alignment Length:	503	Identity:	134/503 - (26%)
Similarity:	243/503 - (48%)	Gaps:	58/503 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 QENQSKTSKTRQYVAAMIICLGAVAA-GTALSWTSPVFPQISAGNESSFNSTTGGIS---NSTSN 94
            ||.:.:..:.:..:.|.:|.:..||. |::..:         ..|.:|.||.:..:.   |||:.
Frog     4 QEKKEEPDERKGRLTATLILVTLVATFGSSFQY---------GYNVASVNSPSPFMKDFYNSTNI 59

  Fly    95 EN-DIRLTDSQKTLVG----SMLPFGALFGALPSGYIADRIGRRYTAMVMDIPFILAWI---TLS 151
            |. ...|.|:..||:.    |:.|.|..||:|..|.:..::||:.|.:..:|..|:..|   |..
Frog    60 ERVGSPLEDAFLTLLWSLTVSLYPLGGFFGSLLVGPLVSKLGRKGTLLFNNIFSIIPAILMGTSV 124

  Fly   152 FANSVGWLYLGRFLIGIATGSFCVVAPMYISEIAETSIRGSLGTLFQLLLTIGILFI------YV 210
            .|.:...:...|..:|:..|....|.|||:.|::..::||::|.:.||::|:|||..      |:
Frog   125 VAKTFEVIIASRLFVGVCAGLSSNVVPMYVGEMSPKNLRGAIGIMPQLMITVGILMAQIFGIRYI 189

  Fly   211 VGALVSWKTLSLLCLIIPILLLVGLFIVPETPVY-LLKNGKRSEANRALKWL--WGDYCNTSNAI 272
            :|....|..|..|..|..:|.|..|...||:|.| ||..|...:|.:||:.|  |.|.  .|...
Frog   190 LGNTEGWPILLALTGIPAVLELAFLPFFPESPRYTLLHKGNEDKAKKALQRLRGWEDV--DSEIK 252

  Fly   273 QAIQNDLDQTGV-DASVKDLFSNRASRNGMVISVLLMVFQQFSGINAVIFFMNEIFESSSTLNPN 336
            :..|.|..:... ..||::|.:.|..|..::..:::.:.||.||||||.::.:.|::|:......
Frog   253 EMYQEDQSEKAEGQLSVRNLCTFRPLRWQLISIIVMNMGQQLSGINAVYYYADSIYKSAGVKEET 317

  Fly   337 V--CTIVVGVVQVIMTLASSLLIEKAGRKILLI-------FSSTIMTVCLAMLGAYNTINRHTDL 392
            :  .|:..|.|.|:||||:..:::..||::||:       .|..::|:.|    .|.|
Frog   318 IQYVTVATGSVNVLMTLAAVFIVDSWGRRVLLLSGFGTCCISCVVLTIAL----VYQT------- 371

  Fly   393 SQSIGWLPLL---CIVLFIVSFSVGYGPIPWMMMGELFMPDVKGIAVSLSVMMNWVCVSLVTWLF 454
              ::.|:|.|   ||:::::..::|..|||:::..|:|....:..|..::..::|:...::..:|
Frog   372 --TVSWMPYLSIACIIIYVIGHAIGPSPIPYVITTEMFRQASRPAAFMIAGSVHWLSNFIIGLIF 434

  Fly   455 GVLNAGGADVPFWFFSAWMGVATAYVAIALQETKGKSASQIQSWLSGR 502
            ..|..|.....|..|:|.......::.|.:.|||||:..::...::.|
Frog   435 EFLMNGLGAYCFILFAAICLATFIFIYIVVPETKGKTFLEVSQLMAKR 482

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1208	NP_001097692.1	MFS	96..482	CDD:119392	112/415 (27%)
CG1208	NP_001097692.1	MFS_1	96..443	CDD:284993	105/376 (28%)
slc2a5	NP_001008187.1	MFS_GLUT_Class2	24..475	CDD:340990	129/474 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910