DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1208 and Slc2a7

DIOPT Version :9

Sequence 1:	NP_001097692.1	Gene:	CG1208 / 40727	FlyBaseID:	FBgn0037386	Length:	502	Species:	Drosophila melanogaster
Sequence 2:	XP_017175793.1	Gene:	Slc2a7 / 435818	MGIID:	3650865	Length:	553	Species:	Mus musculus

Alignment Length:	496	Identity:	130/496 - (26%)
Similarity:	240/496 - (48%)	Gaps:	44/496 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 ENQSKTSKTRQYVAAMIICLGAVAAGTALSWTSPVFPQ--------ISAGNESSFNSTTGG---- 87
            |..:|....|....:.:..||:.:|    :.|||.:|:        :...:....:::.||
Mouse    32 EYLNKDGGQRDRDTSALATLGSASA----AHTSPDYPKCCLWLSLPVWLQHRRDQHTSQGGHKVL 92

  Fly    88 --ISNSTSNENDIRLTDSQKTLV-----GSMLPFGALFGALPSGYIADRIGRRYTAMVMDIPFIL 145
              ..|.|..|......|....|:     .||.|.|.|.|:|..|.:.::.||:.|.::.::..|.
Mouse    93 KSFYNDTHFERHGTFMDESTLLLLWSCTVSMFPLGGLLGSLVVGLMVNKWGRKGTLLINNVFAIT 157

  Fly   146 AWITL---SFANSVGWLYLGRFLIGIATGSFCVVAPMYISEIAETSIRGSLGTLFQLLLTIGILF 207
            :.:.:   ..|.:...:.|.|.|:||..|......|||:.|:|..::||:|||:.::.:.||:|.
Mouse   158 SAVLMGVSKVARAFELIILSRVLVGICAGIAYSTLPMYLGELAPQNLRGALGTMTEVFVIIGVLL 222

  Fly   208 IY------VVGALVSWKTLSLLCLIIPILLLVGLFIVPETPVY-LLKNGKRSEANRALKWLWGDY 265
            ..      ::|....|..|..|..:..::.|:.|...||:|.| |::.|....|.:||:.|.|..
Mouse   223 AQIFSLQAILGNATGWPILLALTGVPAVIQLLSLPFFPESPRYTLIEKGDEETARQALRRLRGQN 287

  Fly   266 CNTSNAIQAIQND--LDQTGVDASVKDLFSNRASRNGMVISVLLMVFQQFSGINAVIFFMNEIFE 328
            .|....::.::.:  .:|.....||.:||:.|..|..::..|:||..||.||||||.::.:.|:
Mouse   288 YNVEAEMEEMRTEERTEQAEGRLSVLNLFTFRPLRWQLISIVVLMAGQQLSGINAVNYYADVIY- 351

  Fly   329 SSSTLNP---NVCTIVVGVVQVIMTLASSLLIEKAGRKILLIFSSTI-MTVCLAMLGAYNTINRH 389
            :|:.::|   ...|:..||:.::|||.|:::||:.||:|||:....| .:.||.:..|....:..
Mouse   352 TSAGVDPTQSQYVTLGSGVINLVMTLVSAVIIERLGRRILLLSGYAICCSACLVLTVALLLQSTA 416

  Fly   390 TDLSQSIGWLPLLCIVLFIVSFSVGYGPIPWMMMGELFMPDVKGIAVSLSVMMNWVCVSLVTWLF 454
            .:||    :|.::|:..:||..|:|..|:|.::..|:.:...:..|.::...::|:...:|...|
Mouse   417 PELS----YLSIVCVFSYIVGHSIGPSPVPSVVRTEIVLQSSRTAAFTVDGAVHWLTNFIVGLTF 477

  Fly   455 GVLNAGGADVPFWFFSAWMGVATAYVAIALQETKGKSASQI 495
            ..:........|..|:....:..||:.:.:.||||::..:|
Mouse   478 PSIQVAIGAYSFLVFAGVCILTAAYIYVVIPETKGRTFVEI 518

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1208	NP_001097692.1	MFS	96..482	CDD:119392	110/406 (27%)
CG1208	NP_001097692.1	MFS_1	96..443	CDD:284993	103/367 (28%)
Slc2a7	XP_017175793.1	MFS_GLUT_Class2	89..518	CDD:340990	117/433 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167834179
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.850