DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1208 and CG10960

DIOPT Version :9

Sequence 1:	NP_001097692.1	Gene:	CG1208 / 40727	FlyBaseID:	FBgn0037386	Length:	502	Species:	Drosophila melanogaster
Sequence 2:	NP_648605.1	Gene:	CG10960 / 39458	FlyBaseID:	FBgn0036316	Length:	539	Species:	Drosophila melanogaster

Alignment Length:	508	Identity:	196/508 - (38%)
Similarity:	285/508 - (56%)	Gaps:	36/508 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 KVVRAMARWWQTVSQEDGDSRNPITYDLLQENQSKTS------KTRQYVAAMIICLGAVAAGTAL 63
            |:|:|        |.....|..|...:.|..|...||      |..|||||:....||.||||.|
  Fly    45 KIVKA--------SDNGRTSSTPHDQENLLGNMVHTSTSNNSQKWPQYVAALAAAGGAFAAGTVL 101

  Fly    64 SWTSPVFPQISAGNESSFNSTTGGISNSTSNENDIRLTDSQKTLVGSMLPFGALFGALPSGYIAD 128
            .||||...:|....|.                .|..:...|.:.|||.:..||....:|.|::.:
  Fly   102 GWTSPAETEIVDRGEG----------------YDFPVDKDQFSWVGSAMTLGAACVCIPIGFLIN 150

  Fly   129 RIGRRYTAMVMDIPFILAWITLSFANSVGWLYLGRFLIGIATGSFCVVAPMYISEIAETSIRGSL 193
            .|||::|.:.:.:||||.|..|.:|.:|..||..||::|||.|:|||.||||..|||:..|||:|
  Fly   151 MIGRKWTMLFLVLPFILGWTMLIWAVNVSMLYASRFILGIAGGAFCVTAPMYTGEIAQKEIRGTL 215

  Fly   194 GTLFQLLLTIGILFIYVVGALVSWKTLSLLCLIIPILLLVGLFIVPETPVYLLKNGKRSEANRAL 258
            |:.|||::||||||:|.|||.|....||::|.|:|::.....|.:||:|.||:...:...|.:::
  Fly   216 GSFFQLMITIGILFVYAVGAGVKIFWLSIICGILPLIFGAIFFFMPESPTYLVSKDRSENAIKSI 280

  Fly   259 KWLWG-DYCNTSNAIQAIQNDLDQTGVDASVKDLFSNRASRNGMVISVLLMVFQQFSGINAVIFF 322
            :||.| :|.......:..:.|.:......:|....:...:|..:.||:.||.|||..|||||||:
  Fly   281 QWLRGKEYDYEPELAELRETDRETKANKVNVWAALNRPVTRKALAISMGLMFFQQVCGINAVIFY 345

  Fly   323 MNEIF-ESSSTLNPNVCTIVVGVVQVIMTLASSLLIEKAGRKILLIFSSTIMTVCLAMLGAYNTI 386
            .:.|| |:::.:.....||::|::||:.|..|:|:::|.||:|||:.|...|.:....:|.|..:
  Fly   346 ASRIFLEANTGIEAEWATILIGIMQVVATFVSTLVVDKLGRRILLLASGISMAISTTAIGVYFFL 410

  Fly   387 NRHTDLSQ--SIGWLPLLCIVLFIVSFSVGYGPIPWMMMGELFMPDVKGIAVSLSVMMNWVCVSL 449
            .:. |.:|  |:||||:..:.|||:.||:||||:||:||||||..|:||.|.||:...||:...:
  Fly   411 QKQ-DAAQVVSLGWLPVASLCLFIIMFSIGYGPVPWLMMGELFATDIKGFAGSLAGTSNWLLAFV 474

  Fly   450 VTWLFGVLNAG-GADVPFWFFSAWMGVATAYVAIALQETKGKSASQIQSWLSG 501
            ||..|..||.| |....||.|:....|...:|..|:.||||||.::||..|:|
  Fly   475 VTKTFVNLNDGLGIGGTFWLFAGLTVVGVIFVYFAVPETKGKSLNEIQQELAG 527

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1208	NP_001097692.1	MFS	96..482	CDD:119392	156/390 (40%)
CG1208	NP_001097692.1	MFS_1	96..443	CDD:284993	142/350 (41%)
CG10960	NP_648605.1	MFS_1	117..474	CDD:284993	144/373 (39%)
CG10960	NP_648605.1	MFS	118..508	CDD:119392	156/390 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45444326
Domainoid	1	1.000	212	1.000	Domainoid score	I87
eggNOG	1	0.900	-	-		E1_KOG0254
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	217	1.000	Inparanoid score	I143
Isobase	1	0.950	-	0	Normalized mean entropy	S2521
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	1	1.000	-	-		FOG0000275
OrthoInspector	1	1.000	-	-		mtm9751
orthoMCL	1	0.900	-	-		OOG6_100060
Panther	1	1.100	-	-	P	PTHR48021
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	11	10.750