DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1208 and CG4797

DIOPT Version :9

Sequence 1:	NP_001097692.1	Gene:	CG1208 / 40727	FlyBaseID:	FBgn0037386	Length:	502	Species:	Drosophila melanogaster
Sequence 2:	NP_726368.2	Gene:	CG4797 / 37770	FlyBaseID:	FBgn0034909	Length:	533	Species:	Drosophila melanogaster

Alignment Length:	510	Identity:	125/510 - (24%)
Similarity:	232/510 - (45%)	Gaps:	62/510 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 ARWWQTVSQEDGDSRNPITYDLLQENQSKTSKTRQYVAAMIICLGAVAAGTALSWTSPVFPQISA 75
            :|...|:.::|.|:.|            :.....|.:|...:.|.:...|..:.:::.:.||:
  Fly    36 SRKLSTIDEQDDDAAN------------RRGMMHQILATCAVLLLSAGCGMPIGFSAILLPQL-- 86

  Fly    76 GNESSFNSTTGGISNSTSNENDIRLTDSQKTLVGSMLPFGALFGALPSGYIADRIGRRYTAMVMD 140
                           ..:|..:|.:.....:.:.|:......||:|.||.:||.:|||.|.::..
  Fly    87 ---------------MDNNSTEIPIDVETGSWIASVHSLATPFGSLLSGPLADYLGRRRTLILSV 136

  Fly   141 IPFILAWITLSFANSVGWLYLGRFLIGIATGSFCVVAPMYISEIAETSIRGSLGTLFQLLLTIGI 205
            ||.:|.|.||:.|.|:..:...|||.|.|||.......:||:|.||.::|..|.....:..:.||
  Fly   137 IPLLLGWSTLAIAKSIKVVIFARFLCGFATGILGGPGQVYIAETAEPNLRSLLIGAPYVAYSSGI 201

  Fly   206 LFIYVVGALVSWKTLSLLCLIIPILLLVGLFIVPETPVYLLKNGKRSEANRALKWLWGDYCNTSN 270
            |.:|.:|:::.|::::....::|:|.:|.:..:||||.:||:||....|.:||.:|.|...:...
  Fly   202 LMVYSLGSMMYWRSVAWCANVLPLLSMVSISFIPETPAWLLRNGHEKRALQALSFLRGSEISAQK 266

  Fly   271 AIQAIQNDLDQ--------TGVDASVKDLFSNRASRNGMVISVLLMVFQQFSGINAVIFF-MNEI 326
            .:    ||:.|        |..:.::..|...|.:...:||.::..:.|.|||...|||: ::.|
  Fly   267 EL----NDMKQRLAKERVTTKTNENIFQLCCQRVAIKPLVIVIVFSLLQMFSGTFIVIFYAVDMI 327

  Fly   327 FESSSTLNPNVCTIVVGVVQVIMTLA-SSLLIEKAGRKILLIFSSTIMTVCLAM----LGAYNTI 386
            .|..:..:.....|...||:||..:. ..:||....|:|:::........||.:    ...::..
  Fly   328 SEFGAEFDSKQAAIATAVVRVICCMVFCVVLIFVRRRRIMIVSGIGSGLFCLVLSVYQYARFDQP 392

  Fly   387 NRHTDLSQSIGWLPLLCIVLFIVSFSVGYGPIPWMMMGELFMPDVK-----GIAVSLSVMMNWVC 446
            ....|:....|     |::.:|: |:.....:|.:|:||||...::     |:..|::|.: ::.
  Fly   393 KMSYDVFVGAG-----CLLGYII-FNTALMVMPGIMIGELFPARIRGRTAGGVFASMNVAL-FIF 450

  Fly   447 VSLVTWLFGVLNAGGADVPFWFFSAWMGVATAYVAIALQETKGKSASQIQSWLSG 501
            ......|..:|...|.   |..|.....:.||::.:...||||:|...|:.:.:|
  Fly   451 AKKFPALQAMLKMRGV---FLVFGVSSFLLTAFMCLFQPETKGRSLEHIEDYFNG 502

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1208	NP_001097692.1	MFS	96..482	CDD:119392	106/404 (26%)
CG1208	NP_001097692.1	MFS_1	96..443	CDD:284993	99/365 (27%)
CG4797	NP_726368.2	MFS	64..484	CDD:119392	111/450 (25%)
CG4797	NP_726368.2	Sugar_tr	89..497	CDD:278511	112/421 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR48021
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.920