DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1208 and Slc2a12

DIOPT Version :9

Sequence 1:	NP_001097692.1	Gene:	CG1208 / 40727	FlyBaseID:	FBgn0037386	Length:	502	Species:	Drosophila melanogaster
Sequence 2:	NP_849265.2	Gene:	Slc2a12 / 353169	MGIID:	3052471	Length:	622	Species:	Mus musculus

Alignment Length:	547	Identity:	134/547 - (24%)
Similarity:	237/547 - (43%)	Gaps:	121/547 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 CLGAVAAGTALSWTSPVFPQISAGNESSFNSTTGGISNSTSN-ENDIRLTDSQKTLVGSMLPFGA 116
            |.|..:..|.|:..:.....:..|.|      .|.||.:... ...:.||..::.:|.|.|..||
Mouse    36 CAGGPSMFTFLTSVTAAISGLLVGYE------LGLISGALLQIRTLLALTCHEQEMVVSSLLIGA 94

  Fly   117 LFGALPSGYIADRIGRRYTAMVMDIPFILAWITLSFANSVGWLYLGRFLIGIATGSFCVVAPMYI 181
            ...:|..|.:.||.|||...::......|..:.|..:.|...|.:||..||::.....:...:||
Mouse    95 FLASLTGGVLIDRYGRRLAIILSSCLLGLGSLVLIMSLSYTLLIMGRVAIGVSISLSSIATCVYI 159

  Fly   182 SEIAETSIRGSLGTLFQLLLTIGILFIYVVG---ALVS--WKTLSLLCLIIPILLLVGLFIVPET 241
            :|||....||.|.:|.:|::..||||.|:..   |.:|  ||.:..|.:.:.:|..:.::.:|.:
Mouse   160 AEIAPQHRRGLLVSLNELMIVTGILFAYISNYAFANISNGWKYMFGLVIPLGVLQAIAMYFLPPS 224

  Fly   242 PVYLLKNGKRSEANRALKWLWGDYCNTSNAIQAIQNDLDQTGVDASVKDLFSNRAS-RNGMVISV 305
            |.:|:..|:...|.:.|:.| ....:|:..:..|::.| :.....|..|||.::.: |..::|.:
Mouse   225 PRFLVMKGQEESAGKVLRKL-RVISDTTEELTLIKSSL-KDEYQYSFWDLFRSKDNMRTRILIGL 287

  Fly   306 LLMVFQQFSGINAVIFFMNEIFES---SSTLNPNVCTIVVGVVQVIMTLASSLLIEKAGRKILLI 367
            .|:.|.|.:|...::|:.:.:.:|   .|....::.:..||||:|:.|:.::||::..|.|..|.
Mouse   288 TLVFFVQTTGQPNILFYASTVLKSVGFQSNEAASLASTGVGVVKVVSTIPATLLVDHIGSKTFLC 352

  Fly   368 FSSTIMTVCLAMLGAYN-TIN--------RHTDLSQSI--------------------------- 396
            ..|::|:..|..:|..| .||        .|:.|:||:
Mouse   353 IGSSVMSASLLTMGIVNLNINMNFTNICRSHSLLNQSLEEFVFYATGNLSISNSSLREHFKRITP 417

  Fly   397 ------------------------------------------------GWLPLLCIVLFIVSFSV 413
                                                            .||.|..:::::.:||:
Mouse   418 YSKGSFMPMGNGMEPKGEMTFTSSLPNAGLSRTEHQGVTDTAVVPAAYKWLSLASLLVYVAAFSI 482

  Fly   414 GYGPIPWMMMGELFMPDVKGIAVSLSVMMNW---VCVSL----VTWLFGVLNAGGADVPFW--FF 469
            |.||:||:::.|:|...::|.|::|:..|||   :.:||    ||.|.|:         .|  |.
Mouse   483 GLGPMPWLVLSEIFPGGIRGRAMALTSSMNWGVNLLISLTFLTVTDLIGL---------SWVCFI 538

  Fly   470 SAWMGVAT-AYVAIALQETKGKSASQI 495
            ...|.:|: |:|.:.:.||||.|..||
Mouse   539 YTIMSLASLAFVVLFIPETKGCSLEQI 565

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1208	NP_001097692.1	MFS	96..482	CDD:119392	118/488 (24%)
CG1208	NP_001097692.1	MFS_1	96..443	CDD:284993	103/439 (23%)
Slc2a12	NP_849265.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..26
		Sugar_tr	48..569	CDD:278511	130/535 (24%)
		MFS	49..>367	CDD:119392	85/325 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167834441
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.840