Protein Alignment CG1208 and SLC2A8

DIOPT Version :10

• Sequence 1: NP_001097692.1
• Gene: CG1208 / 40727
• FlyBaseID: FBgn0037386
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: XP_047279239.1
• Gene: SLC2A8 / 29988
• HGNCID: 13812
• Length: 599
• Species: Homo sapiens
• Alignment Length: 618
• Identity: 171/618 - (27%)
• Similarity: 273/618 - (44%)
• Gaps: 151/618 - (24%)

  Fly    17 VSQEDGDSRNPITYDLLQENQSKTSKTRQYVAAMIICLGAVAAGTALSWTSPVFPQIS------- 74
            ::.||.:...|:   |.....|.....|.::||....||.::.|.||.::||..|.:.
Human     1 MTPEDPEETQPL---LGPPGGSAPRGRRVFLAAFAAALGPLSFGFALGYSSPAIPSLQRAAPPAP 62

  Fly    75 ----------------------------------------------------------------- 74
                                                                             
Human    63 RLDDAAASWFGVRPRARSSRPGTPRPPLGTGIGTLRPPPFPSGQASGPAATTFPHETGIGPLCPP 127

  Fly    75 ---AGNESSFNSTTGGISNSTSNENDIRLTDSQKTLVGS-------------------------- 110
               :|..||.::.|..:..||...:.:.|...:....||
Human   128 SLPSGRASSPSAPTPPLGTSTGPLSPLPLPSGRARGPGSFTSEPAGSGWRGRMGCGFGAPSSAAA 192

  Fly   111 ----MLPFGALFGALPSGYIADRIGRRYTAMVMDIPFILAWITLSFANSVGWLYLGRFLIGIATG 171
                ::..||..|.:..|::.||.||:.:.::..:||:..:..::.|..|..|..||.|.|:|.|
Human   193 RLQAVVTLGAAAGGVLGGWLVDRAGRKLSLLLCSVPFVAGFAVITAAQDVWMLLGGRLLTGLACG 257

  Fly   172 SFCVVAPMYISEIAETSIRGSLGTLFQLLLTIGILFIYVVGALVSWKTLSLLCLIIPILLLVGLF 236
            ...:|||:||||||..::||.||:..||::.:|||..|:.|.::.|:.|::|..:.|.|:|:.:.
Human   258 VASLVAPVYISEIAYPAVRGLLGSCVQLMVVVGILLAYLAGWVLEWRWLAVLGCVPPSLMLLLMC 322

  Fly   237 IVPETPVYLLKNGKRSEANRALKWLWGDYCNTSN-AIQAIQND----LDQTGVDASVKDLFSNRA 296
            .:||||.:||...:|.||..||::|||......: .|.|.|:.    |.|.|:
Human   323 FMPETPRFLLTQHRRQEAMAALRFLWGSEQGWEDPPIGAEQSFHLALLRQPGI------------ 375

  Fly   297 SRNGMVISVLLMVFQQFSGINAVIFFMNEIFESSSTLNPNVCTIVVGVVQVIMTLASSLLIEKAG 361
             ....:|.|.||.|||.||:|||:|:...|||.:...:.::.::||||:||:.|..::|::::||
Human   376 -YKPFIIGVSLMAFQQLSGVNAVMFYAETIFEEAKFKDSSLASVVVGVIQVLFTAVAALIMDRAG 439

  Fly   362 RKILLIFSSTIMTVCLAMLGAYNTINR-------H-----------TDLSQSIGWLPLLCIVLFI 408
            |::||:.|..:|....:..|||..:.:       |           .|.|..:.||.:..:.|||
Human   440 RRLLLVLSGVVMVFSTSAFGAYFKLTQGGPGNSSHVAISAPVSAQPVDASVGLAWLAVGSMCLFI 504

  Fly   409 VSFSVGYGPIPWMMMGELFMPDVKGIAVSLSVMMNWVCVSLVTWLFG----VLNAGGADVPFWFF 469
            ..|:||:|||||::|.|:|...|||:|..:.|:.||:...|||..|.    ||...||   ||..
Human   505 AGFAVGWGPIPWLLMSEIFPLHVKGVATGICVLTNWLMAFLVTKEFSSLMEVLRPYGA---FWLA 566

  Fly   470 SAWMGVATAYVAIALQETKGKSASQIQSWLSGR 502
            ||:...:..:....:.|||||:..||.:...||
Human   567 SAFCIFSVLFTLFCVPETKGKTLEQITAHFEGR 599

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1208	NP_001097692.1	MFS_GLUT6_8_Class3_like	46..494	CDD:340916	161/579 (28%)
SLC2A8	XP_047279239.1	PHA03307	3..>196	CDD:223039	25/195 (13%)
		MFS	36..591	CDD:475125	158/570 (28%)