DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1208 and itr2

DIOPT Version :9

Sequence 1:	NP_001097692.1	Gene:	CG1208 / 40727	FlyBaseID:	FBgn0037386	Length:	502	Species:	Drosophila melanogaster
Sequence 2:	NP_593320.1	Gene:	itr2 / 2541827	PomBaseID:	SPAC20G8.03	Length:	557	Species:	Schizosaccharomyces pombe

Alignment Length:	513	Identity:	138/513 - (26%)
Similarity:	238/513 - (46%)	Gaps:	59/513 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 SQEDGDSRNPITYDLLQENQSKTSKTRQYVAAMIICLGAVAAGTALSWTSPVFPQISAGNESSFN 82
            ::|:.::.:|...::..||.......:  :::.|..|.|||..:.|                .|.
pombe    50 NEEEANATDPQANEVADENGEGFEAEK--ISSWIWVLSAVAGISGL----------------LFG 96

  Fly    83 STTGGISNSTS---NENDIRLTDSQKTLVGSMLPFGALFGALPSGYIADRIGRRYTAMVMDIPFI 144
            ..||.||.:.:   ::....|:..||.|:.|...|.||..|..||::||.:||:...:..|..|:
pombe    97 YDTGVISGALAVLGSDLGHVLSSGQKELITSATSFAALISATTSGWLADWVGRKRLLLCADAIFV 161

  Fly   145 LAWITLSFANSVGWLYLGRFLIGIATGSFCVVAPMYISEIAETSIRGSLGTLFQLLLTIGILFIY 209
            :..:.::.:.:|..:.:|||::|...|...::.||||:|:|...:||.|..::.:.:|.|.|..|
pombe   162 IGSVIMAASRNVAMMVVGRFIVGYGIGLTSLIVPMYITELAPARLRGRLVIIYVVFITGGQLIAY 226

  Fly   210 VVGALV-----SWKTLSLLCLIIPILLLVGLFIVPETPVYLLKNGKRSEANRALKWLWGDYCNTS 269
            .:.|..     .|:.:..:.....:..|:.||..||:|.|||::   :...:..|.|...:....
pombe   227 SLNAAFEHVHQGWRIMFGIGAAPALGQLISLFWTPESPRYLLRH---NHVEKVYKILSRIHPEAK 288

  Fly   270 NAIQAIQNDLDQTGVDA-------------SVKDLFSNRASRNGMVISVLLMVFQQFSGINAVIF 321
            .|..|.:..|.|.||..             |:|.||:..::|..:.|...|..||||||.||:.:
pombe   289 PAEIAYKVSLIQEGVKVDFPEGNKFQHFFHSLKVLFTVPSNRRSLFIGCFLQWFQQFSGTNAIQY 353

  Fly   322 FMNEIFESSSTLNPNVCTIVVGVVQVIMTLASSLLIEKAGRKILLIFSSTIMTVCLAMLG-AYNT 385
            |...||:|....|....:||||....:.|:.:.:.|::.||:.:|:.:|.:|...||:.. ||:.
pombe   354 FSAIIFQSVGFKNSISVSIVVGATNFVFTIVAFMFIDRIGRRRILLCTSAVMIAGLALCAIAYHF 418

  Fly   386 INRHTDLSQSIGW--LPLLCIVLFIVSFSVGYGPIPWMMMGELFMPDVKGIAVSLSVMMNWV--- 445
            :...|..:.:.||  :.|..|::|:.|::.|.|.||| ...|||..:|:.:....|..:|||
pombe   419 LPADTTQNTNSGWQYVVLASIIIFLASYASGIGNIPW-QQAELFPMEVRALGAGFSTAINWVGNL 482

  Fly   446 --CVSLVTWLFGVLNAGGADVPFWFFS--AWMGVATAYVAIALQETKGKSASQIQSWL 499
              ..|.:|.:..:...|    .|..|:  .::|:.|:|  ....|..|.|...|...|
pombe   483 IISASFLTMMESITPTG----TFALFAGFCFVGLVTSY--FTYPELAGMSIENIHKLL 534

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1208	NP_001097692.1	MFS	96..482	CDD:119392	118/413 (29%)
CG1208	NP_001097692.1	MFS_1	96..443	CDD:284993	107/367 (29%)
itr2	NP_593320.1	Sugar_tr	84..534	CDD:278511	132/475 (28%)
itr2	NP_593320.1	MFS	86..519	CDD:119392	127/458 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	179	1.000	Domainoid score	I819
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	184	1.000	Inparanoid score	I1095
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm13833
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X729
TreeFam	0	0.000	Not matched by this tool.
	6	5.860