DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1208 and ght2

DIOPT Version :9

Sequence 1:	NP_001097692.1	Gene:	CG1208 / 40727	FlyBaseID:	FBgn0037386	Length:	502	Species:	Drosophila melanogaster
Sequence 2:	NP_596425.1	Gene:	ght2 / 2539977	PomBaseID:	SPBC4B4.08	Length:	531	Species:	Schizosaccharomyces pombe

Alignment Length:	476	Identity:	107/476 - (22%)
Similarity:	202/476 - (42%)	Gaps:	73/476 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    81 FNSTTGGISNSTSNENDIR---------------LTDSQKTLVGSMLPFGALFGALPSGYIADRI 130
            |.:.||.|...|| ..|.|               |:.:::.|:..|:..|:|||.:.|..||||.
pombe    24 FGADTGSIGGVTS-MRDFRERYADRYDPITDQYSLSSARQGLLTGMVNVGSLFGCIISSPIADRF 87

  Fly   131 GRRYT----------AMVMDIPFILAWITLSFANSVGWLYLGRFLIGIATGSFCVVAPMYISEIA 185
            |:|.:          .:::.:..:.:|:.:..|         :...||..|:..|:||.|.||.|
pombe    88 GKRLSIIGFCAVYIIGIIVQVTAVPSWVQIMVA---------KIWTGIGIGALSVLAPGYQSETA 143

  Fly   186 ETSIRGSLGTLFQLLLTIGILFIYVVG-------ALVSWKTLSLLCLIIPILLLVGLFIVPETPV 243
            ..||||::...:||.:|.||.....:.       ....|:....:.|:..|:.::|:..:||:|.
pombe   144 PPSIRGTVVVTYQLFVTGGIFIAACINMGTHKLHKTAQWRVSIGINLLWGIITMIGILFLPESPR 208

  Fly   244 YLLKNGKRSEANRALK---WLWGDYCNTSNAIQAIQNDLDQ--TGVDASVKDLFSNRASRNGMVI 303
            ||::.||..||.|.|.   .|:.|.....|....:::.:|:  .|...|...:| .:..|....:
pombe   209 YLIQVGKDEEAVRVLSESAELFPDSEEVQNEYHRLKSSIDEEFAGGPCSWASIF-GKDIRYRTFL 272

  Fly   304 SVLLMVFQQFSGINAVIFFMNEIFESSSTLNPNVCTIVVGVVQVIMTLASSLLIEKAGRKILLIF 368
            .:.:|..||.:|.|...::...:.:.:...:|.:..:::..|....|.....::|:.||:..||.
pombe   273 GMFVMSLQQLTGNNYFFYYGFSVMQGAGINSPYLSAMILDAVNFGCTFGGMYVLERFGRRNPLII 337

  Fly   369 SSTIMTVCL---AMLGAYNTINRHTDLSQSIGWLPLLCIVLFIVSFSVGYGPIPWMMMGELFMPD 430
            .....::|.   :.:|:....:::...:...|.:.::...|||..|:..:.|..::::||.:...
pombe   338 GGIWQSICFFIYSAVGSRALYHKNGTSNTRAGAVMIVMACLFIFGFAQTWAPAAYVIVGESYPVR 402

  Fly   431 VKGIAVSLSVMMNWVCVSLVT---------------WLFGVLNAGGADVPFWFFSAWMGVATAYV 480
            .:....:::...||:...|::               ::|...|..||.|.|.|.....|
pombe   403 YRSKCAAVATASNWLWNFLISFFTPFIQASIGFKYGYVFASCNLTGAIVIFLFAKETKG------ 461

  Fly   481 AIALQETKGKSASQIQSWLSG 501
             :.|:|......|.|:.|.||
pombe   462 -LTLEEINELYMSVIKPWESG 481

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1208	NP_001097692.1	MFS	96..482	CDD:119392	94/440 (21%)
CG1208	NP_001097692.1	MFS_1	96..443	CDD:284993	83/386 (22%)
ght2	NP_596425.1	MFS	14..456	CDD:119392	98/442 (22%)
ght2	NP_596425.1	Sugar_tr	15..471	CDD:278511	102/464 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9279
orthoMCL	1	0.900	-	-		OOG6_100060
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.710