Protein Alignment CG1208 and Slc2a4

DIOPT Version :10

• Sequence 1: NP_001097692.1
• Gene: CG1208 / 40727
• FlyBaseID: FBgn0037386
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_033230.2
• Gene: Slc2a4 / 20528
• MGIID: 95758
• Length: 509
• Species: Mus musculus
• Alignment Length: 524
• Identity: 150/524 - (28%)
• Similarity: 248/524 - (47%)
• Gaps: 79/524 - (15%)

  Fly    10 MARWWQTVSQEDGD-SRNPITYDLLQENQSKTSKTRQYVAAMIICLGAVAAGTALSWTSPVFPQI 73
            |...:|.:..:||: .|..:|..|:             :|.....||::..|..:...:.  ||.
Mouse     1 MPSGFQQIGSDDGEPPRQRVTGTLV-------------LAVFSAVLGSLQFGYNIGVINA--PQK 50

  Fly    74 SAGNESSFNST------TGGISNSTSNENDIRLTDS--QKTLVG------SMLPFGALFGALPSG 124
            ..  |.|:|:|      .||             .||  |.||..      ::...|.:..:...|
Mouse    51 VI--EQSYNATWLGRQGPGG-------------PDSIPQGTLTTLWALSVAIFSVGGMISSFLIG 100

  Fly   125 YIADRIGRRYTAMVMDIPFILAWITLSFAN---SVGWLYLGRFLIGIATGSFCVVAPMYISEIAE 186
            .|:..:||:...:..::..:|....:..||   |...|.|||||||..:|....:.|||:.|||.
Mouse   101 IISQWLGRKRAMLANNVLAVLGGALMGLANAAASYEILILGRFLIGAYSGLTSGLVPMYVGEIAP 165

  Fly   187 TSIRGSLGTLFQLLLTIGILFIYV------VGALVSWKTLSLLCLIIPILLLVGLFIVPETP--V 243
            |.:||:||||.||.:.||||...|      :|....|..|..|.::..:|.|:.|...||:|  :
Mouse   166 THLRGALGTLNQLAIVIGILVAQVLGLESMLGTATLWPLLLALTVLPALLQLILLPFCPESPRYL 230

  Fly   244 YLLKNGKRSEANRALKWLWGDYCNTSNAIQAIQNDLDQTGVD--ASVKDLFSNRASRNGMVISVL 306
            |:::| ....|.::||.|.| :.:.|:|:..::::..:...:  .|:..|..:|..|..::|:|:
Mouse   231 YIIRN-LEGPARKSLKRLTG-WADVSDALAELKDEKRKLERERPMSLLQLLGSRTHRQPLIIAVV 293

  Fly   307 LMVFQQFSGINAVIFFMNEIFESSSTLNPNVCTIVVGVVQVIMTLASSLLIEKAGRKILLIFS-- 369
            |.:.||.||||||.::...||||:....|...||..|||..:.||.|.||:|:|||:.|.:..
Mouse   294 LQLSQQLSGINAVFYYSTSIFESAGVGQPAYATIGAGVVNTVFTLVSVLLVERAGRRTLHLLGLA 358

  Fly   370 -----STIMTVCLAMLGAYNTINRHTDLSQSIGWLPLLCIVLFIVSFSVGYGPIPWMMMGELFMP 429
                 :.:|||.|.:|          :...::.::.::.|..|:..|.:|.|||||.::.|||..
Mouse   359 GMCGCAILMTVALLLL----------ERVPAMSYVSIVAIFGFVAFFEIGPGPIPWFIVAELFSQ 413

  Fly   430 DVKGIAVSLSVMMNWVCVSLVTWLFG-VLNAGGADVPFWFFSAWMGVATAYVAIALQETKGKSAS 493
            ..:..|::::...||.|..:|...|. |.:|.|..| |..|:..:.....:..:.:.||:|::..
Mouse   414 GPRPAAMAVAGFSNWTCNFIVGMGFQYVADAMGPYV-FLLFAVLLLGFFIFTFLKVPETRGRTFD 477

  Fly   494 QIQS 497
            ||.:
Mouse   478 QISA 481

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1208	NP_001097692.1	MFS_GLUT6_8_Class3_like	46..494	CDD:340916	141/482 (29%)
Slc2a4	NP_033230.2	Interaction with SRFBP1. /evidence=ECO:0000250|UniProtKB:P14672	7..13		0/5 (0%)
		MFS_GLUT_Class1	26..474	CDD:340989	140/477 (29%)
		Dileucine internalization motif. /evidence=ECO:0000255	489..490