DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1208 and Slc2a3

DIOPT Version :9

Sequence 1:	NP_001097692.1	Gene:	CG1208 / 40727	FlyBaseID:	FBgn0037386	Length:	502	Species:	Drosophila melanogaster
Sequence 2:	XP_006505885.1	Gene:	Slc2a3 / 20527	MGIID:	95757	Length:	495	Species:	Mus musculus

Alignment Length:	462	Identity:	139/462 - (30%)
Similarity:	220/462 - (47%)	Gaps:	57/462 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    81 FNSTTGGIS----------NSTSNENDIRLTDSQK--------TLVGSMLPFGALFGALPSGYIA 127
            |...||.|:          |.|..|   ||.|...        :|..::...|.:.|:...|...
Mouse    26 FGYNTGVINAPETILKDFLNYTLEE---RLEDLPSEGLLTALWSLCVAIFSVGGMIGSFSVGLFV 87

  Fly   128 DRIGRRYTAMVMDIPFILAWITLSF---ANSVGWLYLGRFLIGIATGSFCVVAPMYISEIAETSI 189
            :|.|||.:.:::::..|:|...:.|   |.||..|.|||.||||..|......||||.|::.|::
Mouse    88 NRFGRRNSMLLVNLLAIIAGCLMGFAKIAESVEMLILGRLLIGIFCGLCTGFVPMYIGEVSPTAL 152

  Fly   190 RGSLGTLFQLLLTIGILFI------YVVGALVSWKTLSLLCLIIPILLLVGLFIVPETPVYLLKN 248
            ||:.|||.||.:.:|||..      :::|:...|..|..|.:|..||....|...||:|.:||.|
Mouse   153 RGAFGTLNQLGIVVGILVAQIFGLDFILGSEELWPGLLGLTIIPAILQSAALPFCPESPRFLLIN 217

  Fly   249 GK-RSEANRALKWLWGDYCNTSNAIQAIQNDLDQT-----GVDASVKDLFSNRASRNGMVISVLL 307
            .| ..:|...|:.|||    ||:.:|.||...|::     ....:|.:||.:......::||::|
Mouse   218 KKEEDQATEILQRLWG----TSDVVQEIQEMKDESVRMSQEKQVTVLELFRSPNYVQPLLISIVL 278

  Fly   308 MVFQQFSGINAVIFFMNEIFESSSTLNPNVCTIVVGVVQVIMTLASSLLIEKAGRKIL------- 365
            .:.||.||||||.::...||:.:....|...||..|||..|.|:.|..|:|:|||:.|
Mouse   279 QLSQQLSGINAVFYYSTGIFKDAGVQEPIYATIGAGVVNTIFTVVSLFLVERAGRRTLHMIGLGG 343

  Fly   366 LIFSSTIMTVCLAMLGAYNTINRHTDLSQSIGWLPLLCIVLFIVSFSVGYGPIPWMMMGELFMPD 430
            :...|..||:.|.:...|          :::.::.::.|::::..|.:|.|||||.::.|||...
Mouse   344 MAVCSVFMTISLLLKDDY----------EAMSFVCIVAILIYVAFFEIGPGPIPWFIVAELFSQG 398

  Fly   431 VKGIAVSLSVMMNWVCVSLVTWLFGVLNAGGADVPFWFFSAWMGVATAYVAIALQETKGKSASQI 495
            .:..|::::...||....||..||....|......|..|:|::.....:....:.||||::...|
Mouse   399 PRPAAIAVAGCCNWTSNFLVGMLFPSAAAYLGAYVFIIFAAFLIFFLIFTFFKVPETKGRTFEDI 463

  Fly   496 QSWLSGR 502
            .....|:
Mouse   464 ARAFEGQ 470

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1208	NP_001097692.1	MFS	96..482	CDD:119392	126/415 (30%)
CG1208	NP_001097692.1	MFS_1	96..443	CDD:284993	116/376 (31%)
Slc2a3	XP_006505885.1	MFS_GLUT_Class1	14..458	CDD:340989	136/448 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100060
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810