DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1208 and Slc2a1

DIOPT Version :9

Sequence 1:	NP_001097692.1	Gene:	CG1208 / 40727	FlyBaseID:	FBgn0037386	Length:	502	Species:	Drosophila melanogaster
Sequence 2:	NP_035530.2	Gene:	Slc2a1 / 20525	MGIID:	95755	Length:	492	Species:	Mus musculus

Alignment Length:	421	Identity:	130/421 - (30%)
Similarity:	211/421 - (50%)	Gaps:	68/421 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   115 GALFGALPSGYIADRIGRRYTAMVMDIPFILAWITLSFA---NSVGWLYLGRFLIGIATGSFCVV 176
            |.:.|:...|...:|.|||.:.::|::...:|.:.:.|:   .|...|.||||:||:..|.....
Mouse    75 GGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVAAVLMGFSKLGKSFEMLILGRFIIGVYCGLTTGF 139

  Fly   177 APMYISEIAETSIRGSLGTLFQLLLTIGILFIYVVG--ALVS----WKTLSLLCLIIPILL-LVG 234
            .|||:.|::.|::||:||||.||.:.:|||...|.|  :::.    |..| |..:.||.|| .:.
Mouse   140 VPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLDSIMGNADLWPLL-LSVIFIPALLQCIL 203

  Fly   235 LFIVPETPVYLLKNGKRSEANRA---LKWLWGDYCNTSNAIQAIQNDLDQTG------VDASVKD 290
            |...||:|.:||.|  |:|.|||   ||.|.|    |::..:.:| ::.:.|      ...::.:
Mouse   204 LPFCPESPRFLLIN--RNEENRAKSVLKKLRG----TADVTRDLQ-EMKEEGRQMMREKKVTILE 261

  Fly   291 LFSNRASRNGMVISVLLMVFQQFSGINAVIFFMNEIFESSSTLNPNVCTIVVGVVQVIMTLASSL 355
            ||.:.|.|..::|:|:|.:.||.||||||.::...|||.:....|...||..|:|....|:.|..
Mouse   262 LFRSPAYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEKAGVQQPVYATIGSGIVNTAFTVVSLF 326

  Fly   356 LIEKAGRKILLIFS-------STIMTVCLAMLGAYNTINRHTDLSQSIGWLPLLCIVL---FIVS 410
            ::|:|||:.|.:..       :.:||:.||:|             :.:.|:..|.||.   |:..
Mouse   327 VVERAGRRTLHLIGLAGMAGCAVLMTIALALL-------------ERLPWMSYLSIVAIFGFVAF 378

  Fly   411 FSVGYGPIPWMMMGELFMPDVKGIAVSLSVMMNW-------VCVSLVTWLFGVLNAGGADVPFWF 468
            |.||.|||||.::.|||....:..|::::...||       :|...|..|.|         |:.|
Mouse   379 FEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNWTSNFIVGMCFQYVEQLCG---------PYVF 434

  Fly   469 --FSAWMGVATAYVAIALQETKGKSASQIQS 497
              |:..:.:...:....:.||||::..:|.|
Mouse   435 IIFTVLLVLFFIFTYFKVPETKGRTFDEIAS 465

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1208	NP_001097692.1	MFS	96..482	CDD:119392	124/404 (31%)
CG1208	NP_001097692.1	MFS_1	96..443	CDD:284993	115/356 (32%)
Slc2a1	NP_035530.2	Sugar_tr	19..467	CDD:278511	130/421 (31%)
		MFS	62..450	CDD:119392	124/404 (31%)
		Monosaccharide binding. /evidence=ECO:0000250\|UniProtKB:P11166	282..288		4/5 (80%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	468..492
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167834356
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100060
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.740