DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1208 and F14E5.1

DIOPT Version :9

Sequence 1:	NP_001097692.1	Gene:	CG1208 / 40727	FlyBaseID:	FBgn0037386	Length:	502	Species:	Drosophila melanogaster
Sequence 2:	NP_495772.2	Gene:	F14E5.1 / 184470	WormBaseID:	WBGene00008799	Length:	472	Species:	Caenorhabditis elegans

Alignment Length:	488	Identity:	115/488 - (23%)
Similarity:	217/488 - (44%)	Gaps:	96/488 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    69 VFPQISAGNESSFNSTTGGIS----------NSTSNENDIRLTDSQKTLVGSMLP----FGALFG 119
            :|..|:..:..::..:|..|:          |::.:...:.:|:.:..|:.::..    .|:.||
Worm    13 IFALIAFASNFNYGFSTTYINTSVDEFKTFLNTSLSRRHVIMTEEKYDLIWNVFLNCWFIGSFFG 77

  Fly   120 ALPSGYIADRIGRRYTAMVMD----IPFILAWITLSFANSVGW-----LYLGRFLIGI---ATGS 172
            ...:...::|.|||...::.:    |..||..::|.      |     |.:.||:..|   ||..
Worm    78 VWINSIFSERFGRRVGFLIGNSVAFISSILQCLSLI------WYCPELLIVSRFITSICMAATYQ 136

  Fly   173 FCVVAPMYISEIAETSIRGSLGTLFQL---LLTIGILFI---YVVGALVSWKTLSLLC-LIIPIL 230
            .|:   :::.|.:.|.:|||...|.::   .:|:...|:   |::|:.:.|     || .::|..
Worm   137 SCI---LFLQECSPTHLRGSFSFLSEVSYSSMTMVGSFLGQDYIIGSHLFW-----LCFFVVPFC 193

  Fly   231 LL--VGLFIVPETPVYLL-KNGKRSEANRALKWLWGDYCNTSNAIQAI------QNDLDQTGVDA 286
            |.  :.|||:||||.:|| ...:..||.:::|:..||..:....::.|      :.|..::....
Worm   194 LFFTLILFILPETPKFLLISKDEEEEAIKSVKYYHGDGTDAKQVLEDIRKEAECEQDSSKSTTFQ 258

  Fly   287 SVKDLFSNRASRNGMVISVLLMVFQQFSGINAVI----FFM------NEIFESSSTLNPNVCTIV 341
            .:|:||:.|..|..:::||..:.  ...|:.|::    ||:      :||.|.|:|        .
Worm   259 KMKELFTERHLRMALILSVSALT--NTVGLWALLLSSTFFLENANVESEIAEWSTT--------A 313

  Fly   342 VGVVQVIMTLASSLLIEKAGRKILLIFSSTIMTVCLAMLGAYNTINRHTDLSQSIGWLPLL--CI 404
            :|:..|..|:...::|||.||:.||:..:.:..:.|.....:..|....|        |:.  |:
Worm   314 MGLAYVSGTITGGIVIEKVGRRKLLLLFTFLNNLALIAFVFFAKIRILID--------PMKYGCL 370

  Fly   405 VLFIV---SFSVGYGPIPWMMMGELFMPDVKGIAVSLSVMMNWVCVSLVTW----LFGVLNAGGA 462
            |..|:   ::..|.|||.|.:..||.....:.||.|::..||.|.|.:.|:    |:.|:   |:
Worm   371 VALIIYGYTYGTGVGPISWFISSELVPQKHRSIAQSVAYSMNTVMVVISTFTVLPLYSVI---GS 432

  Fly   463 DVPFWFFSAWMGVATAYVAIALQETKGKSASQI 495
            ......:|....::...:...|.||||:....|
Worm   433 YAFLILYSIPSFISMLILFRYLPETKGREIHDI 465

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1208	NP_001097692.1	MFS	96..482	CDD:119392	104/436 (24%)
CG1208	NP_001097692.1	MFS_1	96..443	CDD:284993	95/393 (24%)
F14E5.1	NP_495772.2	MFS_GLUT_Class1_2_like	14..460	CDD:340915	113/480 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920