DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1208 and ZK829.9

DIOPT Version :9

Sequence 1:	NP_001097692.1	Gene:	CG1208 / 40727	FlyBaseID:	FBgn0037386	Length:	502	Species:	Drosophila melanogaster
Sequence 2:	NP_502272.1	Gene:	ZK829.9 / 178134	WormBaseID:	WBGene00014097	Length:	492	Species:	Caenorhabditis elegans

Alignment Length:	505	Identity:	117/505 - (23%)
Similarity:	220/505 - (43%)	Gaps:	91/505 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 VAAMIICLGAVAAGTALSWTSPVFPQISAGNESSFNSTTGGISNSTSNE--NDIRLTDSQKTLVG 109
            :..::||        :|......||  |..:.:|.|:....::...:|.  ...|..|.::.
Worm    13 IRLLLIC--------SLLTAMTNFP--SGFSHTSVNTAVHKLNEYLNNSFTERYRPLDHEEV--- 64

  Fly   110 SMLPFGA-----LF---GALPSGYIADRIGRRYTAMVMDIPFI-LA---WITLSFANSVGWLYLG 162
            |:|..|.     ||   ||:.|.::.|..||: .|..:.|.|: ||   .:..||......|..|
Worm    65 SLLKSGINSAWYLFQVVGAMSSPFLCDNYGRK-VAFALSIAFMTLAGAMQMLASFTPYSEVLIAG 128

  Fly   163 RFLIGIATGSFCVVAPMYISEIAETSIRGSLGTLFQLLLTIGILFIYVVGALVSWK-----TLSL 222
            |.:..:.:........:|:.||:.:|:||::.:|:    :.|...:.::|.|:..:     :||:
Worm   129 RLIAAVFSPLSDAALILYLQEISPSSLRGTMSSLY----STGYSTMCLLGMLLGHEGLLGHSLSV 189

  Fly   223 LCLIIPIL--LLVGLFI--VPETPVYLLKNGK-RSEANRALKWLWGDYCNTSNAIQAIQ------ 276
            | |.:|::  :|...||  :|:||.:||...| :..|.::|::..|...:.:..|.:::
Worm   190 L-LFVPVIPGILSTAFILWMPDTPKFLLLVKKDKVAALKSLRFFQGSLPDQTLLIDSMEHHHKED 253

  Fly   277 -----NDLDQTGVDASVKDLFSNRASRNGMVISVLLMVFQ-QFSGI--NAVIFFMNEIFESSSTL 333
                 |..::.....||..:......|..|::||...:.. .|..|  |:..||.:...:..::
Worm   254 ANNNNNSEEKADSATSVMHILKKPHLRKAMMLSVSAAILTLPFYPILQNSTFFFTDMGVDMKTS- 317

  Fly   334 NPNVCTIVVGVVQVIMTLASSLLIEKAGRKILLIFSSTIMTVCLAMLGAYNTINRHTDLSQSIGW 398
              .:.:..:.||..|.::.|:|:|:|..|:|||:...:...:.|.:......:::.   |.::|
Worm   318 --QLASSFMMVVLTISSICSTLIIDKLPRRILLLTCGSCTVLFLTIFAVSEQMHQK---SIAMG- 376

  Fly   399 LPLLCIVLFIVSFSVGYGPIPWMMMGELF-MPD-------VKGIAVSLSVMMNWVCV----SLVT 451
               .|.. ||:|:.:|.||:.|.:..||. :.|       |..|...|.|:.|:..:    |:..
Worm   377 ---ACFG-FIMSYGIGVGPVIWSIPPELSPLADRSMMFCLVYSIHSCLVVVTNFATIPLFMSIGA 437

  Fly   452 WLFGVLNAGGADVPFWFFSAWMGVATAYVAIALQETKGKSASQIQSWLSG 501
            :.|.:|.|    :|..|       |..|:.:.|.||.|:....|.:.|.|
Worm   438 FSFVLLFA----IPSAF-------ALVYLLVCLPETSGREIHVIINELKG 476

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1208	NP_001097692.1	MFS	96..482	CDD:119392	101/433 (23%)
CG1208	NP_001097692.1	MFS_1	96..443	CDD:284993	92/390 (24%)
ZK829.9	NP_502272.1	MFS	19..465	CDD:391944	112/486 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S2521
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D524131at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.870