DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1208 and fgt-1

DIOPT Version :9

Sequence 1:	NP_001097692.1	Gene:	CG1208 / 40727	FlyBaseID:	FBgn0037386	Length:	502	Species:	Drosophila melanogaster
Sequence 2:	NP_493982.1	Gene:	fgt-1 / 173525	WormBaseID:	WBGene00019207	Length:	510	Species:	Caenorhabditis elegans

Alignment Length:	526	Identity:	164/526 - (31%)
Similarity:	247/526 - (46%)	Gaps:	77/526 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 TVSQEDGDSRNPITYDLLQENQSKTSKTRQYV-------------AAMIICL---------GAVA 58
            |.|..| .|::|.:|       |....|.|.:             :|.:|.|         |.|.
Worm    12 TASLSD-SSKSPSSY-------STPGTTTQKIIFPDGKLTKCLAFSAFVITLASFQFGYHIGCVN 68

  Fly    59 A--GTALSWTSPVFPQISAGNESSFNSTTGGISNSTSNENDIRLTDSQKTLVGSMLPFGALFGAL 121
            |  |....|       |...::..|:       ...|.||    .|...::..|:...|.:.|.|
Worm    69 APGGLITEW-------IIGSHKDLFD-------KELSREN----ADLAWSVAVSVFAVGGMIGGL 115

  Fly   122 PSGYIADRIGRRYTAMVMDIPFILAWITLSFANSVG---WLYLGRFLIGIATGSFCVVAPMYISE 183
            .||::||::|||......::..:.|...:..|.|||   .:.|||.:||:..|....:.||:::|
Worm   116 SSGWLADKVGRRGALFYNNLLALAAAALMGLAKSVGAYPMVILGRLIIGLNCGFSSALVPMFLTE 180

  Fly   184 IAETSIRGSLGTLFQLLLTIGIL------FIYVVGALVSWKTLSLLCLIIPILLLVGLFIVPETP 242
            |:..::||.||:|.|||:||.||      ..:::|....|..:....::..:|.|..|.:.||:|
Worm   181 ISPNNLRGMLGSLHQLLVTIAILVSQIFGLPHLLGTGDRWPLIFAFTVVPAVLQLALLMLCPESP 245

  Fly   243 VYLLK-NGKRSEANRALKWLWGDYCNTSNAIQAIQNDLDQTGVDASVK--DLFSNRASRNGMVIS 304
            .|.:. .|:|:||..|||.| .|..:.|..|:|:|.:....||....|  |:|.. |....|.|:
Worm   246 KYTMAVRGQRNEAESALKKL-RDTEDVSTEIEAMQEEATAAGVQEKPKMGDMFKG-ALLWPMSIA 308

  Fly   305 VLLMVFQQFSGINAVIFFMNEIFESSSTL--NPNVCTIVVGVVQVIMTLASSLLIE--KAGRKIL 365
            :::|:.||.||||..:|:...||..:...  .|...||.:|.|.|||||.|..|::  |.||:.|
Worm   309 IMMMLAQQLSGINVAMFYSTVIFRGAGLTGNEPFYATIGMGAVNVIMTLISVWLVDHPKFGRRSL 373

  Fly   366 LIFSSTIMTV-CLAMLGAYNTINRHTDLSQS---IGWLPLLCIVLFIVSFSVGYGPIPWMMMGEL 426
            |:...|.|.| .|.::||....|...|...|   ||:     ::||::||:.|.|.|||..:.|:
Worm   374 LLAGLTGMFVSTLLLVGALTIQNSGGDKWASYSAIGF-----VLLFVISFATGPGAIPWFFVSEI 433

  Fly   427 FMPDVKGIAVSLSVMMNWVCVSLVTWLFGVLNAGGADVPFWFFSAWMGVATAYVAIALQETKGKS 491
            |....:|.|.|::||:||....||...|..:|.......|:.||.::.....|....:.||||||
Worm   434 FDSSARGNANSIAVMVNWAANLLVGLTFLPINNLMQQYSFFIFSGFLAFFIFYTWKFVPETKGKS 498

  Fly   492 ASQIQS 497
            ..|||:
Worm   499 IEQIQA 504

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1208	NP_001097692.1	MFS	96..482	CDD:119392	134/405 (33%)
CG1208	NP_001097692.1	MFS_1	96..443	CDD:284993	124/366 (34%)
fgt-1	NP_493982.1	Sugar_tr	50..506	CDD:278511	155/480 (32%)
fgt-1	NP_493982.1	MFS	100..491	CDD:119392	132/397 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100060
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810