DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1208 and slc2a4

DIOPT Version :9

Sequence 1:	NP_001097692.1	Gene:	CG1208 / 40727	FlyBaseID:	FBgn0037386	Length:	502	Species:	Drosophila melanogaster
Sequence 2:	XP_031755513.1	Gene:	slc2a4 / 101731550	XenbaseID:	XB-GENE-5943313	Length:	509	Species:	Xenopus tropicalis

Alignment Length:	441	Identity:	123/441 - (27%)
Similarity:	216/441 - (48%)	Gaps:	38/441 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    78 ESSFNSTTGGISNSTSNENDIRLTDSQKTLVGSMLPFGALFGALPSGYIADRIGRRYTAMVMDIP 142
            |.|:|.:....|:|.|...|..|..:..:|..::...|.:..:|..|.::..:||: .|||::..
Frog    53 EQSYNESWISRSSSGSASIDPGLLRTLWSLSVAIFSIGGMVSSLSVGVVSQWLGRK-RAMVINNV 116

  Fly   143 FILAWITLSF------ANSVGWLYLGRFLIGIATGSFCVVAPMYISEIAETSIRGSLGTLFQLLL 201
            |  |::..||      ..|...:.:||||||:.:|....:.|||:.||:.|.:||::|||.||.|
Frog   117 F--AFLAGSFMGLSQVCQSYEMMIVGRFLIGVYSGLASGLVPMYVGEISPTHLRGAMGTLHQLSL 179

  Fly   202 TIGILFIYVVG-----------ALVSWKTL---SLLCLIIPILLLVGLFIVPETPVYL-LKNGKR 251
            .||||...|:|           ..:.|.||   :|.||::|        ..||:|.:| :...:.
Frog   180 VIGILVAQVLGLELFLGTNTRWPALFWVTLIPAALQCLMLP--------FCPESPRFLYIVCEQE 236

  Fly   252 SEANRALKWLWG--DYCNTSNAIQAIQNDLDQTGVDASVKDLFSNRASRNGMVISVLLMVFQQFS 314
            ::|.::|:.|.|  |..:..:.::..:..:| :....|:..:|.:|..|..::::::|.:.||.|
Frog   237 AQAKKSLRRLTGLPDVTDDLSDMKEEKRQMD-SEPKVSILQIFRSRNYRQPILVAIVLQLSQQLS 300

  Fly   315 GINAVIFFMNEIFESSSTLNPNVCTIVVGVVQVIMTLASSLLIEKAGRKILLIFSSTIMTVCLAM 379
            ||||:.::..:||..:....|...||..|:|....|:.|..|:|:|||:.|.:.....|.||..:
Frog   301 GINAIFYYSTDIFSKAGVEQPIYATIGAGIVNTAFTVVSLFLVERAGRRTLQLLGLAGMIVCALL 365

  Fly   380 LGAYNTINRHTDLSQSIGWLPLLCIVLFIVSFSVGYGPIPWMMMGELFMPDVKGIAVSLSVMMNW 444
            :.|...:....   .|:.:|.:..|..|:..|.:|.|||||.::.|||....:..|::::...||
Frog   366 MTAAMVLQESV---PSLSYLSMAAIFGFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAIAGCTNW 427

  Fly   445 VCVSLVTWLFGVLNAGGADVPFWFFSAWMGVATAYVAIALQETKGKSASQI 495
            ....::...|..:........|..|.|.:.....:....:.||:|:|..:|
Frog   428 TSNFIIGMGFQYVAELCGPYVFLLFGALLFAFLIFTYFRVPETRGRSFDEI 478

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1208	NP_001097692.1	MFS	96..482	CDD:119392	112/408 (27%)
CG1208	NP_001097692.1	MFS_1	96..443	CDD:284993	106/369 (29%)
slc2a4	XP_031755513.1	MFS_GLUT_Class1	26..473	CDD:340989	120/434 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010