Protein Alignment dgrn and Pex10

DIOPT Version :10

• Sequence 1: NP_649596.1
• Gene: dgrn / 40725
• FlyBaseID: FBgn0037384
• Length: 319
• Species: Drosophila melanogaster
• Sequence 2: NP_001035866.1
• Gene: Pex10 / 668173
• MGIID: 2684988
• Length: 324
• Species: Mus musculus
• Alignment Length: 258
• Identity: 58/258 - (22%)
• Similarity: 98/258 - (37%)
• Gaps: 60/258 - (23%)

  Fly    75 PVERDLSVESDSSSATNTSESSVGEASNQLQSPQSNNPLNMANLSVSTEDAHSQIRSLTQDVIQM 139
            |:|::|..:.|:..|:..|....|.:.:..:....::...:      ||.....::.....:.|.
Mouse   110 PLEQELQADGDAPRASQGSLLPGGRSRSGARRWVRHHAATL------TEQQRKALQRAVFILRQG 168

  Fly   140 EAELDRMNRYCEEVVAQIDTFATRTSTPTTRRIRR--------RTS--PVEVIDLSHLDRAPPVR 194
            .|.|.|::.....:.......|.|.:..|..|.||        |||  .:.:|.|.||..:..:|
Mouse   169 FACLHRLHVAWFYIHGTFYHLAKRLAGITYLRTRRLPGEDQKARTSYGLLGLISLLHLVLSMGLR 233

  Fly   195 --SARNRDPDAFIDLCTPEGPRSRTV-NLHSNDSLTILPRRSAENDPVVDLDVASPPKRVNRDID 256
              |.|.:.             |:|.. .||.|    :..|||:..|..|   ..:|
Mouse   234 LYSFRQKQ-------------RARKEWRLHRN----LSHRRSSLEDRAV---CRTP--------- 269

  Fly   257 ESQKEELYKCPICMDSVSKREPVSTKCGHVFCRECIETAIRATHKCPICNKKLTARQFFRIYL 319
                    .|.:|::  .:|...:|.|||:||.|||........:||:|.:|...::.  :||
Mouse   270 --------LCTLCLE--ERRHSTATPCGHLFCWECITEWCNTKTECPLCREKFPPQKL--VYL 320

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dgrn	NP_649596.1	PEX10	<182..308	CDD:227861	33/128 (26%)
		RING_Ubox	264..315	CDD:473075	16/50 (32%)
Pex10	NP_001035866.1	Pex2_Pex12	16..215	CDD:398431	21/110 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	119..139		4/19 (21%)
		HRD1	<228..>309	CDD:227568	28/119 (24%)
		RING-HC_PEX10	271..320	CDD:438190	16/52 (31%)