Protein Alignment dgrn and Rnf4

DIOPT Version :10

• Sequence 1: NP_649596.1
• Gene: dgrn / 40725
• FlyBaseID: FBgn0037384
• Length: 319
• Species: Drosophila melanogaster
• Sequence 2: NP_062055.1
• Gene: Rnf4 / 29274
• RGDID: 3583
• Length: 194
• Species: Rattus norvegicus
• Alignment Length: 185
• Identity: 58/185 - (31%)
• Similarity: 84/185 - (45%)
• Gaps: 37/185 - (20%)

  Fly   165 STPTTRRIRRRTSPVEVIDLSHLDRAPPVRSARNRDPDAFIDLCTPEGPRSRTVNLHSNDSLTIL 229
            |..|.:|.|..||..| |.|    .|.|:....... |..:|| |.|......|:|..|||:.|:
  Rat    17 SRQTQKRTRETTSTPE-ISL----EAEPIELVETVG-DEIVDL-TCESLEPVVVDLTHNDSVVIV 74

  Fly   230 -----PRRSA---ENDPVVDLDVASPPKRVNRDID--------ESQKEE---------LYKCPIC 269
                 |||:.   ..|......|:|..:.:::|.|        .|.|:|         ...||||
  Rat    75 EERRRPRRNGRRLRQDHADSCVVSSDDEELSKDKDVYVTTHTPRSTKDEGTTGLRPSGTVSCPIC 139

  Fly   270 MDSVSK-----REPVSTKCGHVFCRECIETAIRATHKCPICNKKLTARQFFRIYL 319
            ||..|:     |..|||:||||||.:|:..:::..:.||.|.||:..:::..||:
  Rat   140 MDGYSEIVQNGRLIVSTECGHVFCSQCLRDSLKNANTCPTCRKKINHKRYHPIYI 194

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dgrn	NP_649596.1	PEX10	<182..308	CDD:227861	47/155 (30%)
		RING_Ubox	264..315	CDD:473075	23/55 (42%)
Rnf4	NP_062055.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..36		9/23 (39%)
		Required for ubiquitination activity. /evidence=ECO:0000250|UniProtKB:Q9QZS2	1..20		1/2 (50%)
		Mediates interaction with TRPS1. /evidence=ECO:0000250|UniProtKB:Q9QZS2	6..65		17/54 (31%)
		SUMO interaction motif 1. /evidence=ECO:0000269|PubMed:18408734	40..43		0/2 (0%)
		SUMO interaction motif 2. /evidence=ECO:0000269|PubMed:18408734	50..53		0/2 (0%)
		SUMO interaction motif 3. /evidence=ECO:0000269|PubMed:18408734	61..63		0/1 (0%)
		SUMO interaction motif 4. /evidence=ECO:0000269|PubMed:18408734	71..74		0/2 (0%)
		RING-HC_RNF4	131..187	CDD:438195	23/55 (42%)