DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sec20 and bnip1b

DIOPT Version :9

Sequence 1:	NP_001287187.1	Gene:	Sec20 / 40724	FlyBaseID:	FBgn0037383	Length:	227	Species:	Drosophila melanogaster
Sequence 2:	XP_001333725.2	Gene:	bnip1b / 795732	ZFINID:	ZDB-GENE-120203-6	Length:	232	Species:	Danio rerio

Alignment Length:	219	Identity:	88/219 - (40%)
Similarity:	131/219 - (59%)	Gaps:	11/219 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 QDLIDNNLQAKAIIHDILNSRTSIAELEELNEAGRSKLSAIRKSIERLDDWA----RDTADSALA 73
            |::|..:|:.||||.||.......|.|.|||...:.|.|.:|:.|:.::..|    |:|...||.
Zfish    18 QEIIKYDLEIKAIIQDIRECCGPQAVLMELNSTVKEKFSLLRQRIQDMEQMAKEQDRETDKQALL 82

  Fly    74 NEVDDHRDQFSKTLQAFRKANVSTMLEIEKANREELMAITGESELRQRTTTRARHNQGSLVSQEN 138
            :|.:.||.|......|:||||::..|.|:...::||  :.|...:|||..|:.     |||...:
Zfish    83 SETEGHRKQMLSNQMAWRKANLACKLAIDNLEKDEL--LQGGDAVRQRKATKE-----SLVQTSS 140

  Fly   139 DVTEKMLAISRHLSETTQKSAITLETLVASSQNVEATSDELHHTAGSISMSGKLLKKYGRRECTD 203
            |:||.:::|||.:|:..|:|..|:.|||.||:.|:.|::|.....|:|.:..||:.||.|||.||
Zfish   141 DITESLMSISRMMSQQVQQSDETIGTLVTSSRTVQETNEEFKAMTGTIHLGRKLILKYNRRELTD 205

  Fly   204 KMLLFFAFSLFLACVFYIVQKRLF 227
            |:|:|.|.:||||.|.||::||||
Zfish   206 KLLIFLAIALFLATVLYILKKRLF 229

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sec20	NP_001287187.1	Sec20	135..226	CDD:112708	41/90 (46%)
bnip1b	XP_001333725.2	SNARE_SEC20	136..228	CDD:277218	42/91 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170596743
Domainoid	1	1.000	88	1.000	Domainoid score	I7903
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H930
Inparanoid	1	1.050	148	1.000	Inparanoid score	I4368
OMA	1	1.010	-	-		QHG55915
OrthoDB	1	1.010	-	-		D1328108at2759
OrthoFinder	1	1.000	-	-		FOG0004333
OrthoInspector	1	1.000	-	-		otm24455
orthoMCL	1	0.900	-	-		OOG6_103788
Panther	1	1.100	-	-	LDO	PTHR12825
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	12	11.910