DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sec20 and bnip1a

DIOPT Version :9

Sequence 1:	NP_001287187.1	Gene:	Sec20 / 40724	FlyBaseID:	FBgn0037383	Length:	227	Species:	Drosophila melanogaster
Sequence 2:	XP_021328462.1	Gene:	bnip1a / 565822	ZFINID:	ZDB-GENE-081107-44	Length:	229	Species:	Danio rerio

Alignment Length:	219	Identity:	76/219 - (34%)
Similarity:	128/219 - (58%)	Gaps:	10/219 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 QDLIDNNLQAKAIIHDILNSRTSIAELEELNEAGRSKLSAIRKSIERLDDWARDTADSA----LA 73
            |::|..:|:.||::.|:.......::|.:||...:.|.:.:|:.|:.|:..:::....:    |.
Zfish    14 QEIIKFDLELKALVQDVNECTGPQSKLTDLNLIVKEKFNKLRQRIQDLEQMSKEQDKESDKLMLL 78

  Fly    74 NEVDDHRDQFSKTLQAFRKANVSTMLEIEKANREELMAITGESELRQRTTTRARHNQGSLVSQEN 138
            .:|:.||.|......|:||||::..|.|:|..:|:|:. :.:..:|.|..|:.     ||....:
Zfish    79 LKVEGHRKQMLSNQTAWRKANLACKLSIDKLEKEDLLN-SEDMSVRHRKMTKE-----SLAQTSS 137

  Fly   139 DVTEKMLAISRHLSETTQKSAITLETLVASSQNVEATSDELHHTAGSISMSGKLLKKYGRRECTD 203
            |:||.:::|||.:|:..|:|..|:.||..||:.|..|.:|.....|:|.:..||:.||.|||.||
Zfish   138 DITESLMSISRMMSQQVQQSEETMGTLATSSRTVLETHEEFKAMTGTIQLGRKLIIKYNRRELTD 202

  Fly   204 KMLLFFAFSLFLACVFYIVQKRLF 227
            |:|:|.|.:||||.|.||::||||
Zfish   203 KLLIFLALALFLATVLYILKKRLF 226

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sec20	NP_001287187.1	Sec20	135..226	CDD:112708	40/90 (44%)
bnip1a	XP_021328462.1	SNARE_SEC20	133..225	CDD:277218	40/91 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170596744
Domainoid	1	1.000	88	1.000	Domainoid score	I7903
eggNOG	1	0.900	-	-		E1_28N8I
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H930
Inparanoid	1	1.050	148	1.000	Inparanoid score	I4368
OMA	1	1.010	-	-		QHG55915
OrthoDB	1	1.010	-	-		D1328108at2759
OrthoFinder	1	1.000	-	-		FOG0004333
OrthoInspector	1	1.000	-	-		otm24455
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12825
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3048
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	14	13.900