DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42675 and zc2hc1a

DIOPT Version :9

Sequence 1:	NP_001262302.1	Gene:	CG42675 / 40722	FlyBaseID:	FBgn0261561	Length:	427	Species:	Drosophila melanogaster
Sequence 2:	NP_955974.1	Gene:	zc2hc1a / 324412	ZFINID:	ZDB-GENE-030131-3132	Length:	327	Species:	Danio rerio

Alignment Length:	164	Identity:	70/164 - (42%)
Similarity:	98/164 - (59%)	Gaps:	14/164 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   271 CRYCGRHFNTDRLAKHEEVCQRMLTTKRKIFDASKQRIEGTEAAAFNMKSKGNRNRSTYSSAAQQ 335
            |:.|||.|....|.||..:||:....:||:||:.:||.||||.:  .:|....:.:|:.||:...
Zfish    17 CKICGRSFFPKVLKKHVPICQKTAAKRRKVFDSGRQRAEGTEIS--TVKPIKPKLQSSSSSSKSD 79

  Fly   336 KGLTTGVKKNNWRKKHEDFIQSIRAAKQVKAHLARGGKLSDLPPPPPSENPDYVQCPHCGRRFNE 400
            |. ....|::|||:|||:||.:|||||.:...:..||.|.  ||||||.:|||:|||:|.|||.|
Zfish    80 KP-EPPKKQSNWRRKHEEFIATIRAAKSINQVIKDGGPLP--PPPPPSYDPDYIQCPYCQRRFGE 141

  Fly   401 QAAERHIPKC---VNMVHNK------PRNGPPAK 425
            .||:|||..|   .:.:.||      .:..|||:
Zfish   142 NAADRHIKFCKEQASRISNKSKLAGGDKTKPPAR 175

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42675	NP_001262302.1	zf-C2HC_2	271..291	CDD:290624	8/19 (42%)
CG42675	NP_001262302.1	zf-C2HC_2	389..410	CDD:290624	13/20 (65%)
zc2hc1a	NP_955974.1	zf-C2HC_2	13..37	CDD:290624	8/19 (42%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	40..96		21/58 (36%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	108..131		12/24 (50%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	154..271		5/22 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	74	1.000	Domainoid score	I9150
eggNOG	1	0.900	-	-		E1_KOG3940
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004293
OrthoInspector	1	1.000	-	-		oto39067
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2959
SonicParanoid	1	1.000	-	-		X1390
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.840