DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42675 and ZC2HC1B

DIOPT Version :9

Sequence 1:	NP_001262302.1	Gene:	CG42675 / 40722	FlyBaseID:	FBgn0261561	Length:	427	Species:	Drosophila melanogaster
Sequence 2:	NP_001013645.1	Gene:	ZC2HC1B / 153918	HGNCID:	21174	Length:	222	Species:	Homo sapiens

Alignment Length:	155	Identity:	65/155 - (41%)
Similarity:	87/155 - (56%)	Gaps:	19/155 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   271 CRYCGRHFNTDRLAKHEEVCQRMLTTKRKIFDASKQRIEGTEAAAFNMKSKGNRNRSTYSSAAQQ 335
            |..|||.|..|.|.:|..:|:::...|||.|.:.|||::||:.             .|.....|.
Human    18 CEVCGRRFAADVLERHGPICKKLFNRKRKPFSSLKQRLQGTDI-------------PTVKKTPQS 69

  Fly   336 KGLTTGVKKNNWRKKHEDFIQSIRAAKQVKAHLARGGKLSDLPPPPPSENPDYVQCPHCGRRFNE 400
            |  :..|:|:|||::|||||.:||:|||....:..|..|.  ||||||.||||:|.|:|.|||||
Human    70 K--SPPVRKSNWRQQHEDFINAIRSAKQCMLAIKEGRPLP--PPPPPSLNPDYIQRPYCMRRFNE 130

  Fly   401 QAAERHIPKCVNMVHNKPRNGPPAK 425
            .|||||...|.:....:..|  ||:
Human   131 SAAERHTNFCKDQSSRRVFN--PAQ 153

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42675	NP_001262302.1	zf-C2HC_2	271..291	CDD:290624	8/19 (42%)
CG42675	NP_001262302.1	zf-C2HC_2	389..410	CDD:290624	13/20 (65%)
ZC2HC1B	NP_001013645.1	zf-C2HC_2	14..38	CDD:316435	8/19 (42%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	48..78		11/44 (25%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	196..222
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165148256
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3940
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004293
OrthoInspector	1	1.000	-	-		otm41098
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1390
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.740