DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1218 and hpf1

DIOPT Version :9

Sequence 1:	NP_649589.1	Gene:	CG1218 / 40718	FlyBaseID:	FBgn0037377	Length:	449	Species:	Drosophila melanogaster
Sequence 2:	XP_002933368.3	Gene:	hpf1 / 100488348	XenbaseID:	XB-GENE-6034616	Length:	360	Species:	Xenopus tropicalis

Alignment Length:	416	Identity:	131/416 - (31%)
Similarity:	186/416 - (44%)	Gaps:	74/416 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 EVDGAEGKKVAPKRSASSQSGEQKK---EEQTEPVNKDKSNTSASSTEMVNKDTAKGSYEAETEE 94
            ||.|...:.|    .|....|::||   ::..||.:..|.::..|.   |:||
Frog     5 EVRGRGRRPV----MAGGGKGKRKKPAAQQCEEPCDAKKRHSGRSE---VSKD------------ 50

  Fly    95 LHKEAMSNISGKNYMEILEKRIRLSVQKEYDNLCESNEFIRHKFLVEMPPDFYEFWKFVGSLKID 159
                                     ||:|          :..::.:.||.|||:||.|...  ||
Frog    51 -------------------------VQQE----------VEAQYRLTMPEDFYQFWAFCAD--ID 78

  Fly   160 PAKPKDAGLEHLDKVFQLQLVGPFEFLAGKFHGAKLGEPGDYLRHWRFYYDPPEFQTIFVRRG-T 223
            ...|.|.    |.....||||||::.::||....|.....:|..||||||||||||||.|... |
Frog    79 SEAPSDV----LQSSLGLQLVGPYDIISGKHKITKKEAEINYNLHWRFYYDPPEFQTILVGDSKT 139

  Fly   224 GIHYGYWRDVPQDKENLLIARNDSAKGCQFQFVAGNAFDAFLYYLEHDFAATPFSCGQLAGT-KK 287
            ..|.||:||.|:|.. :.:..|::|||||...:..|.|.|...|..:.....  :...|:.| |.
Frog   140 QFHMGYYRDSPEDLP-VFVGANEAAKGCQITQLGDNVFSAVKQYASNKLKEV--TDRNLSSTIKD 201

  Fly   288 AVAKYLS---DNSLELAQLDRLQRERNKRVVAKTFHRAGIVVPFDQKTEVGYRPLAVSDSELKKM 349
            .:||..:   |....|.|.....:.|.|:||.|:||.||:|||.| |.:||||.|..:|..||::
Frog   202 LIAKLTAQAEDLGYSLEQKSATMKRREKKVVTKSFHGAGLVVPVD-KNDVGYRELPETDGNLKRI 265

  Fly   350 LAMLERKDVDNGAAKQAVLEKLQPVANAANIAVDESDFGSALELGIDMFCSGHKELHMLASSLLV 414
            ...:  .:..|...:......:|.:......|.||.|:|...|||:|:||.|....|.:|..||.
Frog   266 CKNI--VEAPNDEKRMKAFAPIQEMITYVQFANDECDYGMGYELGMDLFCYGSYYFHKVARQLLP 328

  Fly   415 PAYSMLSRPQFIAIAKAHMEQRSRED 440
            .||.:|.|..|..|.::|:..|.:|:
Frog   329 LAYKLLERNLFGEIIESHLANRKKEN 354

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1218	NP_649589.1	zf-CCHH	4..25	CDD:287283
CG1218	NP_649589.1	DUF2228	178..428	CDD:287230	95/254 (37%)
hpf1	XP_002933368.3	DUF2228	92..342	CDD:402022	96/255 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H32374
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG49331
OrthoDB	1	1.010	-	-		D1077112at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR13386
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4808
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.060