Protein Alignment Hat1 and hat-1

DIOPT Version :9

• Sequence 1: NP_649587.1
• Gene: Hat1 / 40716
• FlyBaseID: FBgn0037376
• Length: 405
• Species: Drosophila melanogaster
• Sequence 2: NP_499296.2
• Gene: hat-1 / 176458
• WormBaseID: WBGene00044069
• Length: 411
• Species: Caenorhabditis elegans
• Alignment Length: 409
• Identity: 129/409 - (31%)
• Similarity: 223/409 - (54%)
• Gaps: 17/409 - (4%)

  Fly     1 MAQIEKYQDFVIDALEVVDFKLIRDKADINNDALTFHPAMAHQIFGETETIFGYQDLHVRVMYTA 65
            :..:.:.:.::.|.|.||....:::..:|:. |..:.|.|.:|.||:.||||||:||.|.:.:||
 Worm     6 VTNVNRNRRYISDGLAVVKMTFLKNMQEIST-APRYEPEMVYQHFGDEETIFGYEDLEVTIHHTA 69

  Fly    66 GPLHIYLGVDYGKRVNEISGGEIKADDVVSTIAQSLPD---GCYFINLDEFLKTLDKADKFQPFG 127
            ..|:.|:.|.|..:....:|  ::||||:..:..  ||   .......:||.:.|.|...|:|||
 Worm    70 QTLYSYINVSYSSKAKNENG--LEADDVIDKLVH--PDVRPNVLVSGKEEFQQKLIKQKDFKPFG 130

  Fly   128 EKISEYRRVSDDGSERLFEIYQCEYKSSSFLKFFARLQTFILWFVDAASYIDTDDPQWCYFLSYE 192
            |.:.::     :...:.:|:|:...::..|..|..|:||..::|::..|..|..:..|.::..||
 Worm   131 EMVHKF-----ELKGKSYEVYKVAEQTEEFNLFLERIQTLGMFFIECCSLTDNTEDNWLHYFIYE 190

  Fly   193 KYK--NNDGQWQYATAGYTTVYEYYAYPQNKRPRISQMLILPPFQKLGLATQLVESIYRFYQSQK 255
            :..  ..||......|||.|::::|.|....||||:|||:||.::|.|:....:||..|..::..
 Worm   191 RCDTGEGDGSTVANVAGYATLFKFYNYIDRIRPRIAQMLLLPQYRKSGIGASFMESFLRDLRASP 255

  Fly   256 NVVDITVEDPSEDFQRLRNFVDARSCMKLKSFAPGEIVKGFNKEMVREAREALKLNPLQVRKVYE 320
            .|.|:|||.|.:.|..||::||..:||.|:.|||..:.:|::.:|.:.|.|.||::..|.|:|||
 Worm   256 EVFDVTVESPGDQFVSLRDYVDCVNCMTLREFAPENLKRGYSDKMRQAALEKLKISRQQARRVYE 320

  Fly   321 LLRLFYTNVKDEKEYRPYRLEVKKRLNAVYYKQLKDLKKMERFKMDTEMLRARLPTVQQ--RMEQ 383
            :||...||.||::|.:..|::||:||.|...|..:|.|::.......|:.:|....:.:  :...
 Worm   321 ILRYRATNKKDKEELKAQRIDVKRRLYAPMKKSDQDWKRLNLALTPDELRQAACGQMDEETKFST 385

  Fly   384 LHEEYRVVEQEYQSTIAKL 402
            |.:.|..:.:.||.||.::
 Worm   386 LSQNYDRLMEAYQKTIDRI 404

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hat1	NP_649587.1	Hat1_N	10..173	CDD:287379	50/165 (30%)
		Med21	<368..403	CDD:288119	8/37 (22%)
hat-1	NP_499296.2	Hat1_N	15..171	CDD:371026	50/165 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160164744
Domainoid	1	1.000	148	1.000	Domainoid score	I2760
eggNOG	1	0.900	-	-		E1_KOG2696
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2701
Inparanoid	1	1.050	229	1.000	Inparanoid score	I2210
Isobase	1	0.950	-	0	Normalized mean entropy	S2355
OMA	1	1.010	-	-		QHG55168
OrthoDB	1	1.010	-	-		D500261at33208
OrthoFinder	1	1.000	-	-		FOG0004691
OrthoInspector	1	1.000	-	-		oto17579
orthoMCL	1	0.900	-	-		OOG6_102175
Panther	1	1.100	-	-	LDO	PTHR12046
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R551
SonicParanoid	1	1.000	-	-		X3295
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	17	16.790