Protein Alignment kat-60L1 and RPT6

DIOPT Version :10

• Sequence 1: NP_001163523.1
• Gene: kat-60L1 / 40715
• FlyBaseID: FBgn0037375
• Length: 673
• Species: Drosophila melanogaster
• Sequence 2: NP_011467.1
• Gene: RPT6 / 852834
• SGDID: S000003016
• Length: 405
• Species: Saccharomyces cerevisiae
• Alignment Length: 430
• Identity: 122/430 - (28%)
• Similarity: 204/430 - (47%)
• Gaps: 78/430 - (18%)

  Fly   289 MTAALRKSRSV-------------ERLRARKLSTNTQL-NLKHKPVKKNSLDENSNSDDQDATTS 339
            ||||:..|..|             ::::..:|...::. |::....::|:|::.......:....
Yeast     1 MTAAVTSSNIVLETHESGIKPYFEQKIQETELKIRSKTENVRRLEAQRNALNDKVRFIKDELRLL 65

  Fly   340 LEDNSHAQSLATSHNTPKCSPKT--KAKHFSPLGYEVHLVD-------TLEKD------------ 383
            .|..|:...:....:..|...|.  :.|:...:..::::.|       .|..|
Yeast    66 QEPGSYVGEVIKIVSDKKVLVKVQPEGKYIVDVAKDINVKDLKASQRVCLRSDSYMLHKVLENKA 130

  Fly   384 -------ILQRHPCIKWTDVAGLNEAKTILQEAVVLPVIMPEFFK--GIRRPWRGVLMVGPPGTG 439
                   ::::.|...:..|.||.:....::|.:.|||..||.|:  ||.:| :||::.||||||
Yeast   131 DPLVSLMMVEKVPDSTYDMVGGLTKQIKEIKEVIELPVKHPELFESLGIAQP-KGVILYGPPGTG 194

  Fly   440 KTMLAKAVATECGTTFFNVSSSTLTSKYRGESEKLVRLLFEMARFYAPSTIFIDEIDALCASR-- 502
            ||:||:|||......|..||.:.|..||.||..::||.||.|||.:|||.||:||||::.::|
Yeast   195 KTLLARAVAHHTDCKFIRVSGAELVQKYIGEGSRMVRELFVMAREHAPSIIFMDEIDSIGSTRVE 259

  Fly   503 ---GSDSEHEASRRFKAELLIQMDGLNASMQEEKVIMVLAATNHPWDIDEAFRR--RFEKRIYIP 562
               |.|||   .:|...|||.|:||...|    |.|.::.|||....:|.|..|  |.:::|..|
Yeast   260 GSGGGDSE---VQRTMLELLNQLDGFETS----KNIKIIMATNRLDILDPALLRPGRIDRKIEFP 317

  Fly   563 LPNEGTRSALLKLCLKDVCLSPSLNTGIIGDELQGYSGSDISNVCRDASMMAMRRLISGRTPDQI 627
            .|:...|:.:|::..:.:.|:..:|...:.:::.|.||:|:..||.:|.|.|:|.
Yeast   318 PPSVAARAEILRIHSRKMNLTRGINLRKVAEKMNGCSGADVKGVCTEAGMYALRE---------- 372

  Fly   628 KQIRREEVDQPITLQDFQDA--RLRTKKSVSADDVARFEK 665
               ||..|.|    :||:.|  ::..|...:|..||:..|
Yeast   373 ---RRIHVTQ----EDFELAVGKVMNKNQETAISVAKLFK 405

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kat-60L1	NP_001163523.1	P-loop containing Nucleoside Triphosphate Hydrolases	395..561	CDD:476819	75/174 (43%)
		AAA_lid_3	591..629	CDD:465537	10/37 (27%)
		Vps4_C	<638..671	CDD:462762	8/30 (27%)
RPT6	NP_011467.1	PRK03992	12..399	CDD:179699	113/411 (27%)