DRSC/TRiP Functional Genomics Resources

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Protein Alignment kat-60L1 and Fignl2

DIOPT Version :10

Sequence 1:NP_001163523.1 Gene:kat-60L1 / 40715 FlyBaseID:FBgn0037375 Length:673 Species:Drosophila melanogaster
Sequence 2:NP_001201840.1 Gene:Fignl2 / 668225 MGIID:3646919 Length:644 Species:Mus musculus


Alignment Length:578 Identity:131/578 - (22%)
Similarity:215/578 - (37%) Gaps:130/578 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly   171 SNAPGGLGIGGSVPLRSKQRLP------------------------------TQVSAAEVAPQPR 205
            :.|.|..|:|||..:......|                              .|.|||...|.|.
Mouse   119 AGAGGSAGLGGSPVVAGNLTEPLYTGNACGGPSAATEYAAGYGGGYLASGYCAQTSAALAPPPPP 183

  Fly   206 ASQTAQMPFPSQQQDNRWVSSLRRRDPELQPTLPSINSNANSSSLSQSHHGSAGNVGL------- 263
            |   ...|.|               .|...|:.|..|..| :...:|..:|:......       
Mouse   184 A---LLQPAP---------------PPGYGPSAPLYNYPA-AGYAAQPGYGALPPPAAPPAPYLP 229

  Fly   264 AGAGAPTPAASMGTMR---LGRPARASAMTAALRKSRSVE---RLRARKLSTNTQLNLKHKPVKK 322
            :|..||||..:....|   .|.||.|..::.   |.::|:   ..|.||.:        ::|.|.
Mouse   230 SGLAAPTPLPAPAPPRPAPYGFPAAAEGVSL---KRKAVDEGAEARYRKYA--------YEPAKA 283

  Fly   323 NSLDENS--NSDD----------------QDATTSLEDNSHAQSLATSHNTPKCSPKTKAKHFSP 369
            .:.|..|  .:||                :|.|.........:.|.:....|:..|..|.....|
Mouse   284 PAADGASYPAADDTECRGNGFRSKPPGATEDGTGKYGGGGPLKVLGSPAYAPQLEPFDKFPERVP 348

  Fly   370 L--------------GYEVHLVDTLEKDILQRHPCIKWTDVAGLNEAKTILQEAVVLPVIMPEFF 420
            .              |.:...::.:...::...|.::|.||||....|..|:|.::.|::.|...
Mouse   349 AAHGGFAEPSGEPAKGVDPGALELVSSKMVDCGPPVQWADVAGQGALKAALEEELLWPLLRPPAC 413

  Fly   421 KGIRRPWRGVLMVGPPGTGKTMLAKAVATECGTTFFNVSSSTLTSKYRGESEKLVRLLFEMARFY 485
            .|...|.|.||..||.|.||.:|.:.:||..|.|...:..:.|.:....|..:|::..|..||..
Mouse   414 PGSALPPRTVLFFGPRGCGKALLGRCLATRLGATLLRLRGAGLAASGAVEGARLLQAAFAAARCR 478

  Fly   486 APSTIFIDEIDALCASRGSDSEHEASRRFKAELLIQMDGLNASMQEEKVIMVLAATNHPWDIDEA 550
            .|:.:.|.|:|||..:|...:.      .:|.||..:||...:..:.  ::|:..|:.|..:|||
Mouse   479 PPAVLLISELDALLPARDDGAS------LRAPLLTCLDGSCGARADG--VLVVGTTSRPAALDEA 535

  Fly   551 FRRRFEKRIYIPLPNEGTRSALLKLCL-KDVCLSPSLNTGIIGDELQGYSGSDISNVCRDASMMA 614
            .||||..|.|:.||:...|..:|:..| :..|.........:....||:||.::..:|:.|:..|
Mouse   536 TRRRFALRFYVALPDGAARGQILQRALAQQGCALNERELAALVQGTQGFSGGELGQLCQQAAAEA 600

  Fly   615 MRRLISGRTPDQIKQIRREEVDQPITLQDFQDARLRTKKSVSADDVARFEKWMEEYGS 672
            .   |||             :.:|::.:|.:.|..:......:.::....:|.:.|||
Mouse   601 G---ISG-------------LQRPLSYKDVEAALAKVGSRAPSKELDSLVEWDKMYGS 642

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
kat-60L1NP_001163523.1 P-loop containing Nucleoside Triphosphate Hydrolases 395..561 CDD:476819 53/165 (32%)
AAA_lid_3 591..629 CDD:465537 10/37 (27%)
Vps4_C <638..671 CDD:462762 4/32 (13%)
Fignl2NP_001201840.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..36
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 285..323 6/37 (16%)
P-loop containing Nucleoside Triphosphate Hydrolases 388..546 CDD:476819 53/165 (32%)
Blue background indicates that the domain is not in the aligned region.

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