Protein Alignment kat-60L1 and Fignl1

DIOPT Version :10

• Sequence 1: NP_001163523.1
• Gene: kat-60L1 / 40715
• FlyBaseID: FBgn0037375
• Length: 673
• Species: Drosophila melanogaster
• Sequence 2: NP_001412580.1
• Gene: Fignl1 / 60530
• MGIID: 1890648
• Length: 692
• Species: Mus musculus
• Alignment Length: 583
• Identity: 175/583 - (30%)
• Similarity: 267/583 - (45%)
• Gaps: 133/583 - (22%)

  Fly   129 SPFGFTKITATSRPSRNASLKKSSEGGHSSTAERHR--------------PVNNLGSN------- 172
            |||...::...:..::.. |..|:..|.|:||..|.              |..:.|.|
Mouse   200 SPFQSARLPKETNTTKTC-LTSSTSLGESATAAFHMTPLFGNTEKDTQSFPKTSTGLNMFLSNLS 263

  Fly   173 -APGGLGIGGSVPLRSKQRLPTQVSAAEVAPQPRASQTAQMPFPSQQQDNRWVSSLRRRDPELQP 236
             .|.|.    ..|...|....:.:  .::...|..::.     ||:.:|..     ||.|..| |
Mouse   264 CVPSGC----ENPQERKAFNDSDI--IDILSNPTLNKA-----PSKTEDRG-----RREDNSL-P 311

  Fly   237 TLPSINSNA---NSSSLSQSHHGSAGNVGLAGAGAPTPAASMGTMRLGRPARASAMTAALRKSRS 298
            |..:.....   ......||.|.|..:.|:                             ::||..
Mouse   312 TFKTAKEQLWVDQKKKGHQSQHTSKSSNGV-----------------------------MKKSLG 347

  Fly   299 VERLR----------ARKLSTNTQLNLKHKPVKKNSLDENSNSDDQDATTSLEDNSHAQSLATSH 353
            ..|.|          :.|...:.|...|||                        :|.|.|...:|
Mouse   348 AGRSRGIFGKFVPPVSNKQDGSEQHAKKHK------------------------SSRAGSAEPAH 388

  Fly   354 NTPKCSPKTKAKHFSPLGYEVHLVDTLEKDILQRHPCIKWTDVAGLNEAKTILQEAVVLPVIMPE 418
            .|..|     .|:..|     .:|:.:..:|:...|.:.|.|:||:..||..::|.||.|::.|:
Mouse   389 LTDDC-----LKNVEP-----RMVELIMNEIMDHGPPVHWDDIAGVEFAKATIKEIVVWPMMRPD 443

  Fly   419 FFKGIRRPWRGVLMVGPPGTGKTMLAKAVATECGTTFFNVSSSTLTSKYRGESEKLVRLLFEMAR 483
            .|.|:|.|.:|:|:.||||||||::.|.:|::.|.|||::|:|:||||:.||.||:||.||.:||
Mouse   444 IFTGLRGPPKGILLFGPPGTGKTLIGKCIASQSGATFFSISASSLTSKWVGEGEKMVRALFAVAR 508

  Fly   484 FYAPSTIFIDEIDALCASRGSDSEHEASRRFKAELLIQMDGLNASMQEEKVIMVLAATNHPWDID 548
            ...|:.|||||||:|.:.|| |.|||:|||.|.|.|:|:||...|.::.  |:|:.|||.|.:||
Mouse   509 CQQPAVIFIDEIDSLLSQRG-DGEHESSRRIKTEFLVQLDGATTSSEDR--ILVVGATNRPQEID 570

  Fly   549 EAFRRRFEKRIYIPLPNEGTRSALL-KLCLKDVCLSPSLNTGIIGDELQGYSGSDISNVCRDASM 612
            ||.|||..||:|||||....|..:: .|..|:.|......|.::..:..|:||:|::.:||:||:
Mouse   571 EAARRRLVKRLYIPLPEASARKQIVGNLMSKEQCCLSDEETDLVVQQSDGFSGADMTQLCREASL 635

  Fly   613 MAMRRL----ISGRTPDQIKQIRREEVDQPITLQDFQDARLRTKKSVSADDVARFEKWMEEYG 671
            ..:|.|    |:..:|||::         ||...||::|....:.:||..|:..:|.|.|.:|
Mouse   636 GPIRSLHAADIATISPDQVR---------PIAYIDFENAFKTVRPTVSPKDLELYENWNETFG 689

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kat-60L1	NP_001163523.1	P-loop containing Nucleoside Triphosphate Hydrolases	395..561	CDD:476819	86/165 (52%)
		AAA_lid_3	591..629	CDD:465537	14/41 (34%)
		Vps4_C	<638..671	CDD:462762	11/32 (34%)
Fignl1	NP_001412580.1	RecA-like_Figl-1	398..583	CDD:410933	91/192 (47%)
		AAA_lid_3	608..>639	CDD:465537	9/30 (30%)
		Vps4_C	<649..689	CDD:462762	14/48 (29%)