DRSC/TRiP Functional Genomics Resources

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Protein Alignment kat-60L1 and fignl2

DIOPT Version :10

Sequence 1:NP_001163523.1 Gene:kat-60L1 / 40715 FlyBaseID:FBgn0037375 Length:673 Species:Drosophila melanogaster
Sequence 2:NP_001201837.1 Gene:fignl2 / 561837 ZFINID:ZDB-GENE-090313-189 Length:684 Species:Danio rerio


Alignment Length:618 Identity:139/618 - (22%)
Similarity:237/618 - (38%) Gaps:115/618 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly   106 SSTPPTSLSHMARMMDSLILDSLSPFGFTKITATSRPSRNASLKKSSEGGHSSTAERHRPVNNLG 170
            |..||:  ||.:.....::..|..|.|...::|.     |::|..|...|.||.:..|      .
Zfish   127 SLVPPS--SHESLSGPKVVPTSAGPPGSGNVSAV-----NSNLSDSGYSGSSSCSGPH------S 178

  Fly   171 SNAP----GGLGIGGSVPLRSKQRLPTQVSAAEVAPQPRASQTAQMPF----PSQQQDNRWVSSL 227
            |..|    |.....|..|..|....|..:.|.:..|....|.|...|.    ||.......::  
Zfish   179 SEYPPSYNGTYLSSGYCPQPSSALPPASLHALQPNPTLLPSYTTTAPVYNYPPSTYPHQTGLA-- 241

  Fly   228 RRRDPE-LQPTLPSINSNANSSSLSQSHHGSAGNVGLAGAGAPTPAASMGTMRLGRPARASAMTA 291
                |. ..||.|.|.|...|...            :.|.......:|:|....|...:..|...
Zfish   242 ----PSYTHPTAPYIPSPLPSRPT------------VVGGSYGYQNSSVGGSEPGGSLKRKAFEM 290

  Fly   292 ALRKSRSVERLRARKL--------------------------STNTQLNLKHKPVKKNSL--DE- 327
            .|.:..| :..|.||.                          ||:.|.....||..::||  || 
Zfish   291 TLDEEDS-DSSRYRKYSYDPMKTGGDSPYGVTDKAGNGFGTGSTDPQGFKPSKPSSQSSLEGDEV 354

  Fly   328 --------------NSNSDDQDATTSLEDNSHAQSLATSHNTPKCSPKTKAKHFSPLGYEVHLVD 378
                          .:..|.........:|..|:...:.:.:.|.|...|:       .|..:::
Zfish   355 GKYSGLKPLVSPTYGAAGDYSPPAAMTGENGGAEQGFSQNRSQKRSDPMKS-------IEPRMLE 412

  Fly   379 TLEKDILQRHPCIKWTDVAGLNEAKTILQEAVVLPVIMPEFFKGIRRPWRGVLMVGPPGTGKTML 443
            .:.:::....|.:.||::||....|..|:|.::.||:.|.  ..|..| :.:|:.||.|.|||.|
Zfish   413 LVSRELQDCSPAMLWTELAGNCHIKAALEEDLLWPVLRPN--PAIHPP-KTILLFGPQGGGKTTL 474

  Fly   444 AKAVATECGTTFFNVSSSTLTSKYRGESEKLVRLLFEMARFYAPSTIFIDEIDALCASRGSDSEH 508
            |::::::.|.:|:.:|.:||.||.:||:|:|:..||.:|....|:.:.:.|::|:        |.
Zfish   475 ARSLSSQIGASFYRLSCATLASKLKGEAEQLLLTLFSVATARQPAMVLLSEVEAI--------EE 531

  Fly   509 EASRRFKAELLIQMDGLNASMQEEKVIMVLAATNHPWDIDEAFRRRFEKRIYIPLPNEGT-RSAL 572
            |..|:   :|..|::.:..:...:  .:|:..|..|..|.::..|.|.||.:|.||:..| |..|
Zfish   532 EGLRQ---QLQAQLEKIQHNQSNQ--FLVVCTTRRPDLIKDSLLRCFSKRYHIGLPDGNTRRHVL 591

  Fly   573 LKLCLKDVCLSPSLNTGIIGDELQGYSGSDISNVCRDASMMAMRRLISGRTPDQIKQIRREEVDQ 637
            |:......|.........:....:|:|..::..:|:.|...|.   .|...|   .......:..
Zfish   592 LQALAPQGCSLSERELSAVLQRSEGFSVWELLQLCQQALASAS---ASASVP---LHSLPASLSS 650

  Fly   638 PITLQDFQDARLRTKKSVSADDVARFEKWMEEY 670
            | |||||::|..:.:...:..::....:|.:.|
Zfish   651 P-TLQDFENAFCKVRPHSTPKELDTCMEWSKVY 682

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
kat-60L1NP_001163523.1 P-loop containing Nucleoside Triphosphate Hydrolases 395..561 CDD:476819 49/165 (30%)
AAA_lid_3 591..629 CDD:465537 7/37 (19%)
Vps4_C <638..671 CDD:462762 9/33 (27%)
fignl2NP_001201837.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 27..48
PHA03247 <86..287 CDD:223021 41/190 (22%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 99..179 16/64 (25%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 292..403 19/111 (17%)
P-loop containing Nucleoside Triphosphate Hydrolases 429..579 CDD:476819 49/165 (30%)
Blue background indicates that the domain is not in the aligned region.

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