Protein Alignment kat-60L1 and fign

DIOPT Version :10

• Sequence 1: NP_001163523.1
• Gene: kat-60L1 / 40715
• FlyBaseID: FBgn0037375
• Length: 673
• Species: Drosophila melanogaster
• Sequence 2: XP_021334341.1
• Gene: fign / 553599
• ZFINID: ZDB-GENE-050522-339
• Length: 747
• Species: Danio rerio
• Alignment Length: 699
• Identity: 174/699 - (24%)
• Similarity: 309/699 - (44%)
• Gaps: 140/699 - (20%)

  Fly    11 GMGQTAVDPSGGVAQLLNNNSSLYN--QQQQQAAAAQHSFMRQR--------SLTSSNP-VLGRS 64
            |:..:..:||...:...|:.|:|::  ..|:.|::...|::...        :|.|.:| .|..:
Zfish   148 GVASSLSEPSYSSSNCGNHASALHSGIPSQEFASSYNGSYLHSTYSGGQSTPALPSPHPSPLHSA 212

  Fly    65 NALATRPQSPPNVQVEYEVAVPFVPTYRHTPYHSLWDLHQCSSTPPTSLSHMARMMDSLILDSLS 129
            ..|...|..||.:...|..:.|.:.:|.:.|          :..||          .:.:....|
Zfish   213 GLLQPPPPPPPTLVPSYNTSSPNLSSYNYPP----------AGYPP----------QTPVAPGYS 257

  Fly   130 PFGFTKITATSRPSRNAS---LKKSSEGGHSSTAERHRPVNNLGSNAPGGLGIGGSVPLRSKQRL 191
            |.|....:| ..||..|:   |..|:..|:|..:..|.|:      ||..|....:..|:.|...
Zfish   258 PGGAPPPSA-YLPSGIAAPTPLPPSTIPGYSYQSHNHAPI------APTPLNGSSANTLKRKAFY 315

  Fly   192 PTQVSAAEVA------PQPRASQTAQMPFPSQQQDNRWVSSLRRRDPELQPTLPSINSNANSSSL 250
            .|.....:.:      .|.|::|:.....|    ||..|.|.|..         ..:.||::|||
Zfish   316 MTGQGDMDSSYGNFNYSQQRSAQSPMYRMP----DNSLVDSTRGN---------GFDRNADTSSL 367

  Fly   251 S------------QSHHGSAGNVGLAGAGAPTPAASMGTMRLGRPARASAMTAALRKSRSVERLR 303
            :            |...||.....|......:...|:|:||.|               .|..:..
Zfish   368 AFKPTKQSMPTDQQRKFGSQAGRALTPPSYGSSKGSLGSMRSG---------------ESFGKFG 417

  Fly   304 ARKLSTNTQLNLKHKPVKKNSLDENSNSDDQDATTSLEDNSHAQSLATSHNTPKCSPKTKAKHFS 368
            :..:|.:...:.:|.|                         |:...|||.:.|   .:.:.|:
Zfish   418 SPVMSDHGDDSRQHLP-------------------------HSIGTATSSSHP---AEEQLKN-- 452

  Fly   369 PLGYEVHLVDTLEKDILQRHPCIKWTDVAGLNEAKTILQEAVVLPVIMPEFFKGIRRPWRGVLMV 433
               .:..||:.:..:|||:.|.:.|:|:|||..||..:::.|:.|::.|:.|.|:....|.:|:.
Zfish   453 ---SDASLVEMVTTEILQQTPPVDWSDIAGLEMAKATIKDEVLWPILRPDMFSGLATLPRSILLF 514

  Fly   434 GPPGTGKTMLAKAVATECGTTFFNVSSSTLTSKYRGESEKLVRLLFEMARFYAPSTIFIDEIDAL 498
            ||.|||:|:|.:.:|::.|..|..:|.|.|.:|:.||.||:|:..|.:||...||.:||.::|.|
Zfish   515 GPQGTGRTLLGRCMASQLGAAFLLLSGSALVTKWLGEGEKIVQASFLIARCRQPSVVFISDVDLL 579

  Fly   499 CASRGSDSEHEASRRFKAELLIQMDGLNASMQEEKVIMVLAATNHPWDIDEAFRRRFEKRIYIPL 563
            .:|:  .||.....|.|:|||:|:||:.:|.:|.  ::|:.:|:.|.:|||:.||.|.||:.:||
Zfish   580 LSSQ--LSEESPVNRIKSELLLQLDGVLSSPEEH--VLVVCSTSKPEEIDESLRRYFVKRLLVPL 640

  Fly   564 PNEGTRSALLKLCLK--DVCLSPSLNTGIIGDELQGYSGSDISNVCRDASMMAMRRL----ISGR 622
            |:...|..::...|.  :.|||....| ::.....|:||.|:..:|::|.:..:..:    :||.
Zfish   641 PDATARHQIISQLLSQHNYCLSDKEVT-LLVQRTDGFSGLDVVRLCQEALVGPLHGMPGADLSGM 704

  Fly   623 TPDQIKQIRREEVDQPITLQDFQDARLRTKKSVSADDVARFEKWMEEYG 671
            .|.|::         |::.|||::...:.:.|:|..::..:.:|.:.:|
Zfish   705 IPGQMR---------PVSYQDFENVFCKIQPSISQKELDTYTEWNKMFG 744

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kat-60L1	NP_001163523.1	P-loop containing Nucleoside Triphosphate Hydrolases	395..561	CDD:476819	65/165 (39%)
		AAA_lid_3	591..629	CDD:465537	10/41 (24%)
		Vps4_C	<638..671	CDD:462762	7/32 (22%)
fign	XP_021334341.1	PHA03378	<174..300	CDD:223065	32/152 (21%)
		RecA-like_fidgetin	476..638	CDD:410931	65/165 (39%)
		AAA_lid_3	669..>694	CDD:465537	6/24 (25%)
		Vps4_C	<711..744	CDD:462762	7/32 (22%)